RegulonDB

Gene
Name:	infA
Synonym(s):	ECK0875, EG10504, b0884, bypA1
Genome position(nucleotides):	926225 <-- 926443 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	48.4
External database links:

ASAP:	ABE-0003005
CGSC:	17674
ECHOBASE:	EB0499
ECOLIHUB:	infA
OU-MICROARRAY:	b0884
STRING:	511145.b0884
COLOMBOS:	infA

Product

Name:

translation initiation factor IF-1

Synonym(s):

IF1, InfA, protein chain initiation factor IF-1

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

8.25

Isoelectric point:

9.765

Motif(s):

Type	Positions	Sequence
	2 -> 72	AKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
	7 -> 70	IEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFR

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		2 - information transfer --> 2.3 - protein related --> 2.3.2 - translation
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm GO:0005829 - cytosol
	molecular_function	GO:0005515 - protein binding GO:0043022 - ribosome binding GO:0003723 - RNA binding GO:0003743 - translation initiation factor activity GO:0019843 - rRNA binding
	biological_process	GO:0006412 - translation GO:0006413 - translational initiation

Note(s):

Note(s): ...[more].

Evidence:

[IE] Inferred from experiment

Reference(s):

[1] Dai Y., et al., 2017

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

PANTHER:

PDB:

PDB:

PFAM:

PRIDE:

PRODB:

PROSITE:

REFSEQ:

SMART:

SMR:

UNIPROT:

Operon

Name:

infA-serW

Operon arrangement:

Transcription unit	Promoter
serW	serWp2
serW	serWp1
infA	infAp2
infA	infAp1
infA-serW

RNA cis-regulatory element

Attenuation:	Translational

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_1053	925971	reverse	nd	[RS-EPT-CBR]	[2]
promoter	TSS_1054	926139	reverse	nd	[RS-EPT-CBR]	[2]
promoter	TSS_1055	926361	reverse	nd	[RS-EPT-CBR]	[2]
promoter	TSS_1056	926419	reverse	nd	[RS-EPT-CBR]	[2]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Dai Y., Shortreed MR., Scalf M., Frey BL., Cesnik AJ., Solntsev S., Schaffer LV., Smith LM., 2017, Elucidating Escherichia coli Proteoform Families Using Intact-Mass Proteomics and a Global PTM Discovery Database., J Proteome Res 16(11):4156-4165
[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Dai Y., Shortreed MR., Scalf M., Frey BL., Cesnik AJ., Solntsev S., Schaffer LV., Smith LM., 2017, Elucidating Escherichia coli Proteoform Families Using Intact-Mass Proteomics and a Global PTM Discovery Database., J Proteome Res 16(11):4156-4165

[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.