RegulonDB

RegulonDB RegulonDB 11.1: Gene Form

kdpB gene in Escherichia coli K-12 genome

Gene local context to scale (view description)

Gene
Name:	kdpB
Synonym(s):	ECK0685, EG10514, b0697, kac
Genome position(nucleotides):	724988 <-- 727036
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	56.22
External database links:

ASAP:	ABE-0002376
CGSC:	587
ECHOBASE:	EB0509
ECOLIHUB:	kdpB
OU-MICROARRAY:	b0697
STRING:	511145.b0697
COLOMBOS:	kdpB

Product

Name:

K⁺ transporting P-type ATPase subunit KdpB

Synonym(s):

Kac, KdpB

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

72.199

Isoelectric point:

7.819

Motif(s):

Type	Positions	Sequence	Comment
	34 -> 54	PVMFIVWIGSLLTTCISIAMA	UniProt: Helical.
	62 -> 82	ALFSAAISGWLWITVLFANFA	UniProt: Helical.
	111 -> 112	EP	UniProt: In Ref. 1; AAB96336..
	119 -> 282	DKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRM
	159 -> 161	TGE	conserved in type I - V P-type ATPases

Classification:

Multifun Terms (GenProtEC)
		4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.3 - The P-type ATPase (P-ATPase) Superfamily
		6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)
	cellular_component	GO:0031004 - potassium ion-transporting ATPase complex GO:1903103 - potassium:proton antiporter complex GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane
	molecular_function	GO:0005515 - protein binding GO:0016887 - ATP hydrolysis activity GO:0046872 - metal ion binding GO:0000166 - nucleotide binding GO:0005524 - ATP binding GO:0008556 - P-type potassium transmembrane transporter activity GO:0000287 - magnesium ion binding
	biological_process	GO:0006811 - ion transport GO:0006813 - potassium ion transport GO:0071805 - potassium ion transmembrane transport GO:0098655 - cation transmembrane transport

Note(s):

Note(s): ...[more].

Reference(s):

[1] Bramkamp M., et al., 2004
[2] Bramkamp M., et al., 2004
[3] Haupt M., et al., 2004
[4] Haupt M., et al., 2006
[5] Kuhlbrandt W. 2004

External database links:

ALPHAFOLD:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

MINT:

MODBASE:

PANTHER:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PFAM:

PFAM:

PRIDE:

PRODB:

PROSITE:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

kdpFABC

Operon arrangement:

Transcription unit	Promoter
kdpFABC	kdpFp

Transcriptional Regulation
	Display Regulation
Activated by:	KdpE

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References

Reference(s)
[1] Bramkamp M., Altendorf K., 2004, Functional modules of KdpB, the catalytic subunit of the Kdp-ATPase from Escherichia coli., Biochemistry 43(38):12289-96
[2] Bramkamp M., Gassel M., Altendorf K., 2004, FITC binding site and p-nitrophenyl phosphatase activity of the Kdp-ATPase of Escherichia coli., Biochemistry 43(15):4559-67
[3] Haupt M., Bramkamp M., Coles M., Altendorf K., Kessler H., 2004, Inter-domain motions of the N-domain of the KdpFABC complex, a P-type ATPase, are not driven by ATP-induced conformational changes., J Mol Biol 342(5):1547-58
[4] Haupt M., Bramkamp M., Heller M., Coles M., Deckers-Hebestreit G., Herkenhoff-Hesselmann B., Altendorf K., Kessler H., 2006, The holo-form of the nucleotide binding domain of the KdpFABC complex from Escherichia coli reveals a new binding mode., J Biol Chem 281(14):9641-9
[5] Kuhlbrandt W., 2004, Biology, structure and mechanism of P-type ATPases., Nat Rev Mol Cell Biol 5(4):282-95

RegulonDB

Contact us Funding Terms & conditions How to cite