RegulonDB RegulonDB 10.10: Gene Form
   

lamB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

lamB malK malM

Gene      
Name: lamB    Texpresso search in the literature
Synonym(s): ECK4028, EG10528, b4036, malB, malL
Genome position(nucleotides): 4247971 --> 4249311 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.68
External database links:  
ASAP:
 ABE-0013218
CGSC:
 575
ECHOBASE:
 EB0523
ECOLIHUB:
 lamB
OU-MICROARRAY:
 b4036
STRING:
 511145.b4036
COLOMBOS: lamB


Product      
Name: maltose outer membrane channel / phage lambda receptor protein
Synonym(s): LamB, MalB, MalL
Sequence: Get amino acid sequence Fasta Format
Cellular location: outer membrane
Molecular weight: 49.912
Isoelectric point: 4.584
Motif(s):
 
Type Positions Sequence
63 -> 63 C
82 -> 93 SFYFDTNVAYSV
99 -> 99 W
105 -> 115 AFREANVQGKN
209 -> 222 GGTLELGVDYGRAN

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.1 - Channel-type Transporters --> 4.1.B - Beta barrel porins (The Outer Membrane Porin (OMP) Functional Superfamily)
  8 - extrachromosomal --> 8.1 - prophage genes and phage related functions
Gene Ontology Terms (GO)  
cellular_component GO:0009279 - cell outer membrane
GO:0016020 - membrane
GO:0016021 - integral component of membrane
GO:0045203 - integral component of cell outer membrane
GO:0046930 - pore complex
molecular_function GO:0005515 - protein binding
GO:0015288 - porin activity
GO:0015144 - carbohydrate transmembrane transporter activity
GO:0042958 - maltodextrin transmembrane transporter activity
GO:0015481 - maltose transporting porin activity
GO:0001618 - virus receptor activity
biological_process GO:0006811 - ion transport
GO:0006974 - cellular response to DNA damage stimulus
GO:0008643 - carbohydrate transport
GO:0016032 - viral process
GO:0015768 - maltose transport
GO:0015774 - polysaccharide transport
GO:0042956 - maltodextrin transport
GO:0046718 - viral entry into host cell
GO:0034219 - carbohydrate transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Zhang DF., et al., 2018
External database links:  
DIP:
 DIP-10082N
ECOCYC:
 EG10528-MONOMER
ECOLIWIKI:
 b4036
INTERPRO:
 IPR003192
INTERPRO:
 IPR023738
INTERPRO:
 IPR036998
MODBASE:
 P02943
PDB:
 1MPQ
PDB:
 1MPO
PDB:
 1MPN
PDB:
 1MPM
PDB:
 1MAL
PDB:
 1AF6
PFAM:
 PF02264
PRIDE:
 P02943
PRODB:
 PRO_000023072
REFSEQ:
 NP_418460
SMR:
 P02943
UNIPROT:
 P02943


Operon      
Name: malK-lamB-malM         
Operon arrangement:
Transcription unit        Promoter
malK-lamB-malM


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, MalT


Regulation by small RNA    
  Display Regulation
small RNA micA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Zhang DF., Ye JZ., Dai HH., Lin XM., Li H., Peng XX., 2018, Identification of ethanol tolerant outer membrane proteome reveals OmpC-dependent mechanism in a manner of EnvZ/OmpR regulation in Escherichia coli., J Proteomics 179:92-99

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