RegulonDB RegulonDB 10.9: Gene Form
   

panF gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

panF accC prmA yhdT terminator anti-anti-terminator anti-terminator TSS_3596 TSS_3596 TSS_3595 TSS_3595 TSS_3594 TSS_3594 TSS_3593 TSS_3593 TSS_3592 TSS_3592 TSS_3591 TSS_3591 yhdTp yhdTp

Gene      
Name: panF    Texpresso search in the literature
Synonym(s): ECK3245, EG10685, b3258
Genome position(nucleotides): 3407607 --> 3409058 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
54.34
External database links:  
ASAP:
ABE-0010695
CGSC:
10818
ECHOBASE:
EB0679
ECOLIHUB:
panF
OU-MICROARRAY:
b3258
STRING:
511145.b3258
COLOMBOS: panF


Product      
Name: pantothenate:Na+ symporter
Synonym(s): PanF, PanF sodium/pantothenate SSS transporter
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 51.717
Isoelectric point: 9.897
Motif(s):
 
Type Positions Sequence
233 -> 253 ILSPAFMTSFWVLVCFGVIGL
446 -> 466 YLGFHPIVPSLLLSLLAFLVG
302 -> 302 T
36 -> 432 YFLGSRSMGGIVLAMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGFRASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQTIDPQLVTPQGADDILSPAFMTSFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIGTIVVAILMFGMHLAGALGRAVIPDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATIIKDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMIIWLNLLAFGGLEAVFLWPLVLGLYWERANAKGALSAMIVG
124 -> 144 VWLASLSLLVAFVGAMTVQFI

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.3 - cofactors, small molecule carriers --> 1.5.3.5 - Coenzyme A and its modification
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015293 - symporter activity
GO:0015081 - sodium ion transmembrane transporter activity
GO:0022857 - transmembrane transporter activity
GO:0015233 - pantothenate transmembrane transporter activity
biological_process GO:0036376 - sodium ion export across plasma membrane
GO:0006811 - ion transport
GO:0006814 - sodium ion transport
GO:0015887 - pantothenate transmembrane transport
GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-10439N
ECOCYC:
PANF-MONOMER
ECOLIWIKI:
b3258
INTERPRO:
IPR011849
INTERPRO:
IPR038377
INTERPRO:
IPR018212
INTERPRO:
IPR001734
PFAM:
PF00474
PRIDE:
P16256
PRODB:
PRO_000023492
PROSITE:
PS50283
PROSITE:
PS00457
PROSITE:
PS00456
REFSEQ:
NP_417724
UNIPROT:
P16256


Operon      
Name: yhdT-panF-prmA         
Operon arrangement:
Transcription unit        Promoter
yhdT-panF-prmA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3591 3408793 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3592 3408983 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3593 3409040 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3594 3409063 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3595 3409159 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3596 3409381 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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