RegulonDB

Gene
Name:	phnF
Synonym(s):	ECK4095, EG10715, b4102
Genome position(nucleotides):	4321697 <-- 4322422
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	61.85
External database links:

ASAP:	ABE-0013435
CGSC:	34547
ECHOBASE:	EB0709
ECOLIHUB:	phnF
OU-MICROARRAY:	b4102
STRING:	511145.b4102
COLOMBOS:	phnF

Product

Name:

putative transcriptional regulator PhnF

Synonym(s):

PhnF

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

27.621

Isoelectric point:

8.639

Motif(s):

Type	Positions	Sequence	Comment
	11 -> 78	PTRYQEIAAKLEQELRQHYRCGDYLPAEQQLAARFEVNRHTLRRAIDQLVEKGWVQRRQGVGVLVLMR	UniProt: HTH gntR-type.
	14 -> 75	YQEIAAKLEQELRQHYRCGDYLPAEQQLAARFEVNRHTLRRAIDQLVEKGWVQRRQGVGVLV
	38 -> 57	EQQLAARFEVNRHTLRRAID	UniProt: H-T-H motif.
	96 -> 235	DQGSHPTSEKLLSVLRPASGHVADALGITEGENVIHLRTLRRVNGVALCLIDHYFADLTLWPTLQRFDSGSLHDFLREQTGIALRRSQTRISARRAQAKECQRLEIPNMSPLLCVRTLNHRDGESSPAEYSVSLTRADMI

Classification:

Multifun Terms (GenProtEC)
		1 - metabolism --> 1.8 - metabolism of other compounds --> 1.8.1 - phosphorous metabolism
		2 - information transfer --> 2.2 - RNA related --> 2.2.2 - Transcription related
		3 - regulation --> 3.1 - type of regulation --> 3.1.2 - transcriptional level --> 3.1.2.3 - repressor
Gene Ontology Terms (GO)
	cellular_component	GO:0005829 - cytosol
	molecular_function	GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity
	biological_process	GO:0006355 - regulation of transcription, DNA-templated GO:0015716 - organic phosphonate transport

Note(s):

Note(s): ...[more].

Evidence:

[COMP-AINF-FN-FROM-SEQ] Automated inference of function from sequence

Reference(s):

[1] Aravind L., et al., 2003
[2] Gorelik M., et al., 2006
[3] Rigali S., et al., 2002

External database links:

ALPHAFOLD:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PDB:

PFAM:

PFAM:

PRIDE:

PRINTS:

PROSITE:

REFSEQ:

SMART:

SMART:

SMR:

SWISSMODEL:

UNIPROT:

Transcriptional Regulation
	Display Regulation
Activated by:	PhoB

Reference(s)
[1] Aravind L., Anantharaman V., 2003, HutC/FarR-like bacterial transcription factors of the GntR family contain a small molecule-binding domain of the chorismate lyase fold., FEMS Microbiol Lett 222(1):17-23
[2] Gorelik M., Lunin VV., Skarina T., Savchenko A., 2006, Structural characterization of GntR/HutC family signaling domain., Protein Sci 15(6):1506-11
[3] Rigali S., Derouaux A., Giannotta F., Dusart J., 2002, Subdivision of the helix-turn-helix GntR family of bacterial regulators in the FadR, HutC, MocR, and YtrA subfamilies., J Biol Chem 277(15):12507-15