RegulonDB RegulonDB 11.1: Gene Form
   

queA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

tgt queA acpH Fis ppGpp terminator anti-terminator anti-anti-terminator yajCp yajCp TSS_511 TSS_511 TSS_510 TSS_510 tgtp tgtp queAp queAp

Gene      
Name: queA    Texpresso search in the literature
Synonym(s): ECK0399, EG10812, b0405, tsaA
Genome position(nucleotides): 425011 --> 426081
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.15
External database links:  
ASAP:
 ABE-0001411
CGSC:
 29889
ECHOBASE:
 EB0805
ECOLIHUB:
 queA
OU-MICROARRAY:
 b0405
STRING:
 511145.b0405
COLOMBOS: queA


Product      
Name: tRNA preQ134 S-adenosylmethionine ribosyltransferase-isomerase
Synonym(s): QueA, TsaA
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 39.431
Isoelectric point: 4.863
Motif(s):
 
Type Positions Sequence Comment
4 -> 343 TDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFI

 
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.2 - RNA related --> 2.2.3 - RNA modification
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0016740 - transferase activity
GO:0016853 - isomerase activity
GO:0051075 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity
biological_process GO:0009314 - response to radiation
GO:0008616 - queuosine biosynthetic process
GO:0002099 - tRNA wobble guanine modification
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P0A7F9
DIP:
 DIP-47972N
ECOCYC:
 EG10812-MONOMER
ECOLIWIKI:
 b0405
INTERPRO:
 IPR003699
INTERPRO:
 IPR036100
INTERPRO:
 IPR042118
INTERPRO:
 IPR042119
PANTHER:
 PTHR30307
PFAM:
 PF02547
PRIDE:
 P0A7F9
PRODB:
 PRO_000023668
REFSEQ:
 NP_414939
SMR:
 P0A7F9
UNIPROT:
 P0A7F9


Operon      
Name: queA         
Operon arrangement:
Transcription unit        Promoter
queA


Transcriptional Regulation      
Display Regulation             
Activated by: Fis


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_510 426062 forward nd [RS-EPT-CBR] [1]
  promoter TSS_511 427204 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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