RegulonDB RegulonDB 11.1: Gene Form
   

rplW gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

rplB rplC rplD rplW TSS_3818 TSS_3818 TSS_3817 TSS_3817 TSS_3816 (cluster) TSS_3816 (cluster) TSS_3815 TSS_3815 TSS_3814 TSS_3814 TSS_3813 TSS_3813 TSS_3812 TSS_3812 TSS_3811 (cluster) TSS_3811 (cluster) TSS_3810 TSS_3810 TSS_3809 (cluster) TSS_3809 (cluster) TSS_3808 TSS_3808 TSS_3807 (cluster) TSS_3807 (cluster)

Gene      
Name: rplW    Texpresso search in the literature
Synonym(s): ECK3305, EG10883, b3318
Genome position(nucleotides): 3451382 <-- 3451684
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
48.18
External database links:  
ASAP:
ABE-0010856
CGSC:
244
ECHOBASE:
EB0876
ECOLIHUB:
rplW
OU-MICROARRAY:
b3318
STRING:
511145.b3318
COLOMBOS: rplW


Product      
Name: 50S ribosomal subunit protein L23
Synonym(s): RplW
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,ribosome
Molecular weight: 11.199
Isoelectric point: 10.687
Motif(s):
 
Type Positions Sequence Comment
9 -> 95 KVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDF
16 -> 18 VSE UniProt: Strongly reduces trigger factor binding..
18 -> 18 E UniProt: Binds normally to ribosomes; strongly reduces trigger factor binding..
51 -> 53 FEV UniProt: No effect on trigger factor binding..
52 -> 52 E UniProt: No effect on trigger factor binding..

 

Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.3 - protein related --> 2.3.2 - translation
  2 - information transfer --> 2.3 - protein related --> 2.3.8 - ribosomal proteins
  6 - cell structure --> 6.6 - ribosomes
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005840 - ribosome
GO:0022625 - cytosolic large ribosomal subunit
molecular_function GO:0003735 - structural constituent of ribosome
GO:0005515 - protein binding
GO:0003723 - RNA binding
GO:0019843 - rRNA binding
biological_process GO:0006412 - translation
GO:0000027 - ribosomal large subunit assembly
GO:0002181 - cytoplasmic translation
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
P0ADZ0
DIP:
DIP-35972N
ECOCYC:
EG10883-MONOMER
ECOLIWIKI:
b3318
INTERPRO:
IPR013025
INTERPRO:
IPR001014
INTERPRO:
IPR012677
INTERPRO:
IPR012678
MODBASE:
P0ADZ0
PDB:
1ML5
PDB:
2J28
PDB:
2RDO
PDB:
2VRH
PDB:
3BBX
PDB:
3IY9
PDB:
3J45
PDB:
3J46
PDB:
3J5L
PDB:
3J7Z
PDB:
3J8G
PDB:
3J9Y
PDB:
3J9Z
PDB:
3JA1
PDB:
3JBU
PDB:
3JBV
PDB:
3JCD
PDB:
3JCE
PDB:
3JCJ
PDB:
3JCN
PDB:
4CSU
PDB:
4U1U
PDB:
4U1V
PDB:
4U20
PDB:
4U24
PDB:
4U25
PDB:
4U26
PDB:
4U27
PDB:
4UY8
PDB:
4V47
PDB:
4V48
PDB:
4V4H
PDB:
4V4Q
PDB:
4V4V
PDB:
4V4W
PDB:
4V50
PDB:
4V52
PDB:
4V53
PDB:
4V54
PDB:
4V55
PDB:
4V56
PDB:
4V57
PDB:
4V5B
PDB:
4V5H
PDB:
4V5Y
PDB:
4V64
PDB:
4V65
PDB:
4V66
PDB:
4V69
PDB:
4V6C
PDB:
4V6D
PDB:
4V6E
PDB:
4V6K
PDB:
4V6L
PDB:
4V6M
PDB:
4V6N
PDB:
4V6O
PDB:
4V6P
PDB:
4V6Q
PDB:
4V6R
PDB:
4V6S
PDB:
4V6T
PDB:
4V6V
PDB:
4V6Y
PDB:
4V6Z
PDB:
4V70
PDB:
4V71
PDB:
4V72
PDB:
4V73
PDB:
4V74
PDB:
4V75
PDB:
4V76
PDB:
4V77
PDB:
4V78
PDB:
4V79
PDB:
4V7A
PDB:
4V7B
PDB:
4V7C
PDB:
4V7D
PDB:
4V7I
PDB:
4V7S
PDB:
4V7T
PDB:
4V7U
PDB:
4V7V
PDB:
4V85
PDB:
4V89
PDB:
4V9C
PDB:
4V9D
PDB:
4V9O
PDB:
4V9P
PDB:
4WF1
PDB:
4WOI
PDB:
4WWW
PDB:
4YBB
PDB:
5ADY
PDB:
5AFI
PDB:
5AKA
PDB:
5GAD
PDB:
5GAE
PDB:
5GAF
PDB:
5GAG
PDB:
5GAH
PDB:
5H5U
PDB:
5IQR
PDB:
5IT8
PDB:
5J5B
PDB:
5J7L
PDB:
5J88
PDB:
5J8A
PDB:
5J91
PDB:
5JC9
PDB:
5JTE
PDB:
5JU8
PDB:
5KCR
PDB:
5KCS
PDB:
5KPS
PDB:
5KPV
PDB:
5KPW
PDB:
5KPX
PDB:
5L3P
PDB:
5LZA
PDB:
5LZB
PDB:
5LZC
PDB:
5LZD
PDB:
5LZE
PDB:
5LZF
PDB:
5MDV
PDB:
5MDW
PDB:
5MDY
PDB:
5MDZ
PDB:
5MGP
PDB:
5NCO
PDB:
5NP6
PDB:
5NWY
PDB:
5O2R
PDB:
5U4I
PDB:
5U9F
PDB:
5U9G
PDB:
5UYK
PDB:
5UYL
PDB:
5UYM
PDB:
5UYN
PDB:
5UYP
PDB:
5UYQ
PDB:
5WDT
PDB:
5WE4
PDB:
5WE6
PDB:
5WFK
PDB:
6BU8
PDB:
6BY1
PDB:
6C4I
PDB:
6ENF
PDB:
6ENJ
PDB:
6ENU
PDB:
6FU8
PDB:
6GBZ
PDB:
6GC0
PDB:
6GC4
PDB:
6GC6
PDB:
6GC7
PDB:
6GC8
PDB:
6GWT
PDB:
6GXM
PDB:
6GXN
PDB:
6GXO
PDB:
6GXP
PDB:
6H4N
PDB:
6H58
PDB:
6HRM
PDB:
6I0Y
PDB:
6I7V
PDB:
6O9J
PDB:
6O9K
PDB:
6OFX
PDB:
6OG7
PDB:
6ORE
PDB:
6ORL
PDB:
6OST
PDB:
6OT3
PDB:
6OUO
PDB:
6Q97
PDB:
6Q98
PDB:
6Q9A
PDB:
6QUL
PDB:
6S0K
PDB:
6SZS
PDB:
6TBV
PDB:
6TC3
PDB:
6VWL
PDB:
6VWM
PDB:
6VWN
PDB:
6WD6
PDB:
6WDB
PDB:
6WDC
PDB:
6WDD
PDB:
6WDE
PDB:
6WDF
PDB:
6WDG
PDB:
6WDH
PDB:
6WDI
PDB:
6WDJ
PDB:
6WDK
PDB:
6WDL
PDB:
6WDM
PDB:
6WNT
PDB:
6WNV
PDB:
6WNW
PDB:
6XZ7
PDB:
6XZA
PDB:
6XZB
PDB:
6Y69
PDB:
6YS3
PDB:
6YSR
PDB:
6YSS
PDB:
6YST
PDB:
6YSU
PDB:
6ZTJ
PDB:
6ZTL
PDB:
6ZTM
PDB:
6ZTN
PDB:
6ZTO
PDB:
6ZTP
PDB:
6ZU1
PDB:
7BV8
PDB:
7JSS
PDB:
7JSW
PDB:
7JSZ
PDB:
7JT1
PDB:
7JT2
PDB:
7JT3
PFAM:
PF00276
PRIDE:
P0ADZ0
PRODB:
PRO_000023829
PROSITE:
PS00050
REFSEQ:
NP_417777
SMR:
P0ADZ0
SWISSMODEL:
P0ADZ0
UNIPROT:
P0ADZ0


Operon      
Name: rpsJ-rplCDWB-rpsS-rplV-rpsC-rplP-rpmC-rpsQ         
Operon arrangement:
Transcription unit        Promoter
rpsJ-rplCDWB-rpsS-rplV-rpsC-rplP-rpmC-rpsQ


Transcriptional Regulation      
Display Regulation             
Activated by: FNR
Repressed by: ArcA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3807 (cluster) 3450543 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3808 3451410 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3809 (cluster) 3451437 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3810 3451529 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3811 (cluster) 3451535 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3812 3451962 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3813 3451965 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3814 3451991 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3815 3451997 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3816 (cluster) 3452000 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3817 3452125 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3818 3452609 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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