RegulonDB RegulonDB 11.1: Gene Form
   

yhhA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ggt ugpC ugpQ yhhA terminator anti-terminator anti-anti-terminator terminator ugpQp1 ugpQp1 TSS_4057 TSS_4057 yhhAp4 yhhAp4 yhhAp6 yhhAp6

Gene      
Name: yhhA    Texpresso search in the literature
Synonym(s): ECK3432, EG11184, b3448
Genome position(nucleotides): 3586943 --> 3587383
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
51.47
External database links:  
ASAP:
ABE-0011262
ECHOBASE:
EB1171
ECOLIHUB:
yhhA
OU-MICROARRAY:
b3448
STRING:
511145.b3448
COLOMBOS: yhhA


Product      
Name: DUF2756 domain-containing protein YhhA
Synonym(s): YhhA
Sequence: Get amino acid sequence Fasta Format
Molecular weight: 16.624
Isoelectric point: 11.491
Motif(s):
 
Type Positions Sequence Comment
1 -> 17 MKRLLILTALLPFVGFA
18 -> 146 QPINTLNNPNQPGYQIPSQQRMQTQMQTQQIQQKGMLNQQLKTQTQLQQQHLENQINNNSQRVLQSQPGERNPARQQMLPNTNGGMLNSNRNPDSSLNQQHMLPERRNGDMLNQPSTPQPDIPLKTIGP UniProt: Uncharacterized protein YhhA.
27 -> 54 NQPGYQIPSQQRMQTQMQTQQIQQKGML UniProt: Disordered; Sequence Annotation Type: region of interest.
70 -> 120 ENQINNNSQRVLQSQPGERNPARQQMLPNTNGGMLNSNRNPDSSLNQQHML UniProt: Polar residues; Sequence Annotation Type: compositionally biased region.

 

Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
molecular_function GO:0005515 - protein binding
Note(s): Note(s): ...[more].
Reference(s): [1] Laager FM., et al., 2009
External database links:  
ALPHAFOLD:
P0ADX7
DIP:
DIP-47985N
ECOCYC:
EG11184-MONOMER
ECOLIWIKI:
b3448
INTERPRO:
IPR020158
PFAM:
PF10956
PRIDE:
P0ADX7
REFSEQ:
NP_417905
UNIPROT:
P0ADX7


Operon      
Name: yhhA         
Operon arrangement:
Transcription unit        Promoter
yhhA


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yhhAp6 3586729 forward nd [COMP-AINF] [2]
  promoter yhhAp4 3586919 forward nd [COMP-AINF] [2]
  promoter TSS_4057 3586920 forward nd [RS-EPT-CBR] [3]
  promoter ugpQp1 3588300 reverse nd [COMP-AINF] [2]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Laager FM., Becker NM., Park SH., Soh KS., 2009, Effects of Lac operon activation, deletion of the Yhha gene, and the removal of oxygen on the ultra-weak photon emission of Escherichia coli., Electromagn Biol Med 28(3):240-9

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


RegulonDB