RegulonDB RegulonDB 10.9: Gene Form
   

ybhA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

modC pgl ybhA ybhAp6 ybhAp6 pglp2 pglp2 ybhAp10 ybhAp10 TSS_938 (cluster) TSS_938 (cluster)

Gene      
Name: ybhA    Texpresso search in the literature
Synonym(s): ECK0755, EG11239, b0766
Genome position(nucleotides): 797613 <-- 798431 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
51.53
External database links:  
ASAP:
ABE-0002607
CGSC:
37794
ECHOBASE:
EB1221
ECOLIHUB:
ybhA
OU-MICROARRAY:
b0766
STRING:
511145.b0766
COLOMBOS: ybhA


Product      
Name: pyridoxal phosphate/fructose-1,6-bisphosphate phosphatase
Synonym(s): YbhA
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 30.201
Isoelectric point: 5.804
Motif(s):
 
Type Positions Sequence
43 -> 44 TG
6 -> 267 IALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFI

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.27 - pyridoxal 5'-phosphate salvage
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016787 - hydrolase activity
GO:0046872 - metal ion binding
GO:0016773 - phosphotransferase activity, alcohol group as acceptor
GO:0016791 - phosphatase activity
GO:0050308 - sugar-phosphatase activity
GO:0000287 - magnesium ion binding
GO:0033883 - pyridoxal phosphatase activity
biological_process GO:0032361 - pyridoxal phosphate catabolic process
GO:0016311 - dephosphorylation
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
EG11239-MONOMER
ECOLIWIKI:
b0766
INTERPRO:
IPR000150
INTERPRO:
IPR006379
INTERPRO:
IPR023214
INTERPRO:
IPR036412
MODBASE:
P21829
PFAM:
PF08282
PRIDE:
P21829
PROSITE:
PS01228
PROSITE:
PS01229
REFSEQ:
NP_415287
SMR:
P21829
UNIPROT:
P21829


Operon      
Name: ybhA         
Operon arrangement:
Transcription unit        Promoter
ybhA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_938 (cluster) 798458 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [1]
  promoter ybhAp10 798537 reverse Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter pglp2 798539 forward Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter ybhAp6 798592 reverse Similarity to the consensus
Read more >
[ICWHO] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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