RegulonDB

Gene
Name:	rsfS
Synonym(s):	ECK0630, EG11255, b0637, rsfA, ybeB
Genome position(nucleotides):	668719 <-- 669036 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	51.26
External database links:

ASAP:	ABE-0002183
ECHOBASE:	EB1235
ECOLIHUB:	ybeB
OU-MICROARRAY:	b0637
STRING:	511145.b0637
COLOMBOS:	rsfS

Product

Name:

ribosomal silencing factor RsfS

Synonym(s):

RsfA, RsfS, YbeB

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

11.582

Isoelectric point:

4.304

Motif(s):

Type	Positions	Sequence
	10 -> 104	VIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTSSRHVMSIADHVVQESRAAGLLPLGVEGENSADWIVVDLGDVIVHVMQEESRRLYELEKLW

Classification:

Multifun Terms (GenProtEC)
		2 - information transfer --> 2.3 - protein related --> 2.3.2 - translation
		3 - regulation --> 3.1 - type of regulation --> 3.1.3 - posttranscriptional --> 3.1.3.1 - translation attenuation and efficiency
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm GO:0005829 - cytosol
	molecular_function	GO:0005515 - protein binding GO:0043023 - ribosomal large subunit binding
	biological_process	GO:0006417 - regulation of translation GO:0017148 - negative regulation of translation GO:0042256 - mature ribosome assembly GO:0090071 - negative regulation of ribosome biogenesis

Note(s):

Note(s): ...[more].

Evidence:

[HIFS] Human inference of function from sequence
[IDA] Inferred from direct assay

Reference(s):

[1] Chen SS., et al., 2013
[2] Hauser R., et al., 2012
[3] Walbot V., et al., 1979

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

PANTHER:

PFAM:

PRIDE:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

rsfS-rlmH-mrdAB-rlpA

Operon arrangement:

Transcription unit	Promoter
rsfS-rlmH-mrdAB-rlpA	rsfSp

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_760	668468		reverse	nd	[RS-EPT-CBR]	[4]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Chen SS., Williamson JR., 2013, Characterization of the ribosome biogenesis landscape in E. coli using quantitative mass spectrometry., J Mol Biol 425(4):767-79
[2] Hauser R., Pech M., Kijek J., Yamamoto H., Titz B., Naeve F., Tovchigrechko A., Yamamoto K., Szaflarski W., Takeuchi N., Stellberger T., Diefenbacher ME., Nierhaus KH., Uetz P., 2012, RsfA (YbeB) proteins are conserved ribosomal silencing factors., PLoS Genet 8(7):e1002815
[3] Walbot V., Coe EH., 1979, Nuclear gene iojap conditions a programmed change to ribosome-less plastids in Zea mays., Proc Natl Acad Sci U S A 76(6):2760-2764
[4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.