RegulonDB

Gene
Name:	ivbL
Synonym(s):	ECK3663, EG11275, b3672
Genome position(nucleotides):	3852890 <-- 3852988 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	58.59
External database links:

ASAP:	ABE-0012002
ECHOBASE:	EB1253
ECOLIHUB:	ivbL
OU-MICROARRAY:	b3672
STRING:	511145.b3672
COLOMBOS:	ivbL

Product

Name:

ilvBN operon leader peptide

Synonym(s):

IvbL

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

3.206

Isoelectric point:

11.652

Motif(s):

Type	Positions	Sequence
	1 -> 32	MTTSMLNAKLLPTAPSAAVVVVRVVVVVGNAP

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.18 - isoleucine/valine
Gene Ontology Terms (GO)
	cellular_component	GO:0005829 - cytosol
	biological_process	GO:0008652 - cellular amino acid biosynthetic process GO:0009082 - branched-chain amino acid biosynthetic process GO:0009099 - valine biosynthetic process

Note(s):

Note(s): ...[more].

Evidence:

[IDA] Inferred from direct assay

Reference(s):

[1] Friden P., et al., 1982

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PFAM:

PRIDE:

REFSEQ:

UNIPROT:

Operon

Name:

ivbL-ilvBN-uhpABC

Operon arrangement:

Transcription unit	Promoter
uhpB	uhpBp
ivbL	ivbLp
ivbL-ilvBN	ivbLp
ivbL-ilvBN-uhpABC
uhpABC

Transcriptional Regulation
	Display Regulation
Activated by:	CRP

RNA cis-regulatory element

Attenuation:	Transcriptional

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_4251	3853016		reverse	nd	[RS-EPT-CBR]	[2]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Friden P., Newman T., Freundlich M., 1982, Nucleotide sequence of the ilvB promoter-regulatory region: a biosynthetic operon controlled by attenuation and cyclic AMP., Proc Natl Acad Sci U S A 79(20):6156-60
[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Friden P., Newman T., Freundlich M., 1982, Nucleotide sequence of the ilvB promoter-regulatory region: a biosynthetic operon controlled by attenuation and cyclic AMP., Proc Natl Acad Sci U S A 79(20):6156-60

[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.