RegulonDB RegulonDB 11.1: Gene Form
   

gluQ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

pcnB gluQ dksA folK DksA-ppGpp DksA-ppGpp DksA-ppGpp DksA-ppGpp ppGpp ppGpp gluQp1 gluQp1 pcnBp4 pcnBp4 pcnBp2 pcnBp2 pcnBp3 pcnBp3 pcnBp pcnBp pcnBp1 pcnBp1

Gene      
Name: gluQ    Texpresso search in the literature
Synonym(s): ECK0143, EG11362, b0144, yadB
Genome position(nucleotides): 159186 <-- 160112
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 53.61
External database links:  
ASAP:
 ABE-0000497
ECHOBASE:
 EB1337
ECOLIHUB:
 yadB
OU-MICROARRAY:
 b0144
STRING:
 511145.b0144
COLOMBOS: gluQ


Product      
Name: glutamyl-Q tRNAAsp synthetase
Synonym(s): GluQ, YadB
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 34.868
Isoelectric point: 6.927
Motif(s):
 
Type Positions Sequence Comment
19 -> 23 RFAPS UniProt: Glutamate binding; Sequence Annotation Type: region of interest.
22 -> 32 PSPSGELHFGS UniProt: 'HIGH' region; Sequence Annotation Type: short sequence motif.
238 -> 242 KLSKQ UniProt: 'KMSKS' region; Sequence Annotation Type: short sequence motif.

 
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.2 - RNA related --> 2.2.3 - RNA modification
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0046872 - metal ion binding
GO:0016874 - ligase activity
GO:0004812 - aminoacyl-tRNA ligase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0008270 - zinc ion binding
GO:0004818 - glutamate-tRNA ligase activity
biological_process GO:0006400 - tRNA modification
GO:0043039 - tRNA aminoacylation
GO:0006424 - glutamyl-tRNA aminoacylation
GO:0002097 - tRNA wobble base modification
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P27305
DIP:
 DIP-11180N
ECOCYC:
 EG11362-MONOMER
ECOLIWIKI:
 b0144
INTERPRO:
 IPR020058
INTERPRO:
 IPR014729
INTERPRO:
 IPR000924
INTERPRO:
 IPR022380
MODBASE:
 P27305
PDB:
 1NZJ
PDB:
 4A91
PFAM:
 PF00749
PRIDE:
 P27305
PRINTS:
 PR00987
PRODB:
 PRO_000022814
REFSEQ:
 NP_414686
SMR:
 P27305
UNIPROT:
 P27305


Operon      
Name: sfsA-dksA-gluQ         
Operon arrangement:
Transcription unit        Promoter
dksA-yadB
dksA-yadB
dksA-gluQ
sfsA-dksA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter gluQp1 160143 reverse nd [COMP-AINF] [1]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

RegulonDB