RegulonDB

Gene
Name:	fliT
Synonym(s):	ECK1925, EG11389, b1926
Genome position(nucleotides):	2005713 --> 2006078 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	51.64
External database links:

ASAP:	ABE-0006411
CGSC:	30739
ECHOBASE:	EB1362
ECOLIHUB:	fliT
OU-MICROARRAY:	b1926
STRING:	511145.b1926
COLOMBOS:	fliT

Shine dalgarno
Sequence:	tctttgattcAGGACCcagtctgATG

Product

Name:

flagellar biosynthesis protein FliT

Synonym(s):

FliT

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

13.829

Isoelectric point:

4.431

Motif(s):

Type	Positions	Sequence
	21 -> 106	MLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVDPSTTMQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSVLSAY
	60 -> 98	MQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSV
	1 -> 50	MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHL

Classification:

Multifun Terms (GenProtEC)
		1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.12 - flagellum
		2 - information transfer --> 2.3 - protein related --> 2.3.4 - chaperoning, repair (refolding)
		5 - cell processes --> 5.3 - motility, chemotaxis, energytaxis (aerotaxis, redoxtaxis etc)
		6 - cell structure --> 6.4 - flagella
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm GO:0005829 - cytosol
	molecular_function	GO:0005515 - protein binding
	biological_process	GO:0006457 - protein folding GO:0071973 - bacterial-type flagellum-dependent cell motility GO:0044781 - bacterial-type flagellum organization GO:1902209 - negative regulation of bacterial-type flagellum assembly

Note(s):

Note(s): ...[more].

Evidence:

[IMP] Inferred from mutant phenotype

Reference(s):

[1] Kawagishi I., et al., 1992

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PFAM:

PRIDE:

PRODB:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

fliDST

Operon arrangement:

Transcription unit	Promoter
fliDST	fliDp2
fliDST	fliDp1

Transcriptional Regulation
	Display Regulation
Activated by:	FlhDC

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_2266	2006132		forward	nd	[RS-EPT-CBR]	[2]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Kawagishi I., Muller V., Williams AW., Irikura VM., Macnab RM., 1992, Subdivision of flagellar region III of the Escherichia coli and Salmonella typhimurium chromosomes and identification of two additional flagellar genes., J Gen Microbiol 138 ( Pt 6):1051-65
[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Kawagishi I., Muller V., Williams AW., Irikura VM., Macnab RM., 1992, Subdivision of flagellar region III of the Escherichia coli and Salmonella typhimurium chromosomes and identification of two additional flagellar genes., J Gen Microbiol 138 ( Pt 6):1051-65

[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.