RegulonDB RegulonDB 11.1: Gene Form
   

dadX gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

dadA dadX ymgM cvrA Lrp Lrp

Gene      
Name: dadX    Texpresso search in the literature
Synonym(s): ECK1178, EG11408, alnA, alnB, b1190, dadB
Genome position(nucleotides): 1238879 --> 1239949
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 57.98
External database links:  
ASAP:
 ABE-0003997
CGSC:
 883
ECHOBASE:
 EB1380
ECOLIHUB:
 dadX
OU-MICROARRAY:
 b1190
STRING:
 511145.b1190
COLOMBOS: dadX


Product      
Name: alanine racemase 2
Synonym(s): AlnA, AlnB, DadB, DadX, alanine racemase 2, PLP-binding, alanine racemase, catabolic
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 38.845
Isoelectric point: 7.059
Motif(s):
 
Type Positions Sequence Comment
9 -> 217 LDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASP
172 -> 172 A UniProt: In Ref. 1; AAC36881..
215 -> 215 A UniProt: In Ref. 1; AAC36881..
232 -> 354 VMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRVPVV
281 -> 281 P UniProt: In Ref. 1; AAC36881..

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.3 - amino acids
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.17 - alanine
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0003824 - catalytic activity
GO:0016853 - isomerase activity
GO:0030170 - pyridoxal phosphate binding
GO:0008784 - alanine racemase activity
GO:0042803 - protein homodimerization activity
biological_process GO:0006522 - alanine metabolic process
GO:0019480 - L-alanine oxidation to pyruvate via D-alanine
GO:0030632 - D-alanine biosynthetic process
External database links:  
ALPHAFOLD:
 P29012
DIP:
 DIP-9395N
ECOCYC:
 ALARACECAT-MONOMER
ECOLIWIKI:
 b1190
INTERPRO:
 IPR020622
INTERPRO:
 IPR029066
INTERPRO:
 IPR011079
INTERPRO:
 IPR009006
INTERPRO:
 IPR001608
INTERPRO:
 IPR000821
MODBASE:
 P29012
PFAM:
 PF01168
PFAM:
 PF00842
PRIDE:
 P29012
PRINTS:
 PR00992
PRODB:
 PRO_000022397
PROSITE:
 PS00395
REFSEQ:
 NP_415708
SMART:
 SM01005
SMR:
 P29012
SWISSMODEL:
 P29012
UNIPROT:
 P29012


Operon      
Name: dadAX         
Operon arrangement:
Transcription unit        Promoter
dadAX
dadAX
dadAX


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: CRP, Lrp


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB