Gene
Name:	holC
Synonym(s):	ECK4252, EG11413, b4259
Genome position(nucleotides):	4483837 <-- 4484280 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	54.05
External database links:

ASAP:	ABE-0013948
CGSC:	31456
ECHOBASE:	EB1385
ECOLIHUB:	holC
OU-MICROARRAY:	b4259
STRING:	511145.b4259
COLOMBOS:	holC

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_5103	4483498	reverse	nd	[RS-EPT-CBR]	[6]
promoter	TSS_5106	4483936	reverse	nd	[RS-EPT-CBR]	[6]
promoter	TSS_5107	4483996	reverse	nd	[RS-EPT-CBR]	[6]

Reference(s)
[1] Carter JR., Franden MA., Lippincott JA., McHenry CS., 1993, Identification, molecular cloning and characterization of the gene encoding the chi subunit of DNA polymerase III holoenzyme of Escherichia coli., Mol Gen Genet 241(3-4):399-408
[2] Nagar N., Ecker N., Loewenthal G., Avram O., Ben-Meir D., Biran D., Ron E., Pupko T., 2021, Harnessing Machine Learning To Unravel Protein Degradation in Escherichia coli., mSystems 6(1)
[3] Sargentini NJ., Gularte NP., Hudman DA., 2016, Screen for genes involved in radiation survival of Escherichia coli and construction of a reference database., Mutat Res 793-794:1-14
[4] Watanabe K., Tominaga K., Kitamura M., Kato JI., 2016, Systematic identification of synthetic lethal mutations with reduced-genome Escherichia coli: synthetic genetic interactions among yoaA, xthA and holC related to survival from MMS exposure., Genes Genet Syst 91(3):183-188
[5] Xiao H., Crombie R., Dong Z., Onrust R., O'Donnell M., 1993, DNA polymerase III accessory proteins. III. holC and holD encoding chi and psi., J Biol Chem 268(16):11773-8
[6] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.