RegulonDB RegulonDB 11.1: Gene Form
   

qorA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

dnaB qorA pspG pspH ppGpp terminator anti-terminator alrp2 alrp2 alrp1 alrp1 qorAp qorAp TSS_4887 (cluster) TSS_4887 (cluster) dnaBp dnaBp

Gene      
Name: qorA    Texpresso search in the literature
Synonym(s): ECK4043, EG11492, b4051, hcz, hzc, qor
Genome position(nucleotides): 4263248 <-- 4264231
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 53.05
External database links:  
ASAP:
 ABE-0013262
CGSC:
 36654
ECHOBASE:
 EB1455
ECOLIHUB:
 qor
OU-MICROARRAY:
 b4051
STRING:
 511145.b4051
COLOMBOS: qorA


Product      
Name: putative quinone oxidoreductase 1
Synonym(s): Hcz, Hzc, Qor, QorA
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 35.172
Isoelectric point: 8.58
Motif(s):
 
Type Positions Sequence Comment
29 -> 88 NEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAAGIVSKVGSGVKHIKAGDRVVYA
42 -> 46 FIDTY UniProt: NADP.
152 -> 279 GVGLIACQWAKALGAKLIGTVGTAQKAQSALKAGAWQVINYREEDLVERLKEITGGKKVRVVYDSVGRDTWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREELTEA
173 -> 177 GTAQK UniProt: NADP.
238 -> 241 FGNS UniProt: NADP.

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.4 - energy production/transport --> 1.4.3 - electron carriers
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0005515 - protein binding
GO:0016491 - oxidoreductase activity
GO:0008270 - zinc ion binding
GO:0003960 - NADPH:quinone reductase activity
GO:0042803 - protein homodimerization activity
biological_process GO:0034599 - cellular response to oxidative stress
Note(s): Note(s): ...[more].
Reference(s): [1] Trauchessec M., et al., 2014
External database links:  
ALPHAFOLD:
 P28304
DIP:
 DIP-10631N
ECOCYC:
 QOR-MONOMER
ECOLIWIKI:
 b4051
INTERPRO:
 IPR036291
INTERPRO:
 IPR002364
INTERPRO:
 IPR020843
INTERPRO:
 IPR013154
INTERPRO:
 IPR011032
INTERPRO:
 IPR013149
MODBASE:
 P28304
PDB:
 1QOR
PFAM:
 PF08240
PFAM:
 PF00107
PRIDE:
 P28304
PROSITE:
 PS01162
REFSEQ:
 NP_418475
SMART:
 SM00829
SMR:
 P28304
UNIPROT:
 P28304


Operon      
Name: qorA         
Operon arrangement:
Transcription unit        Promoter
qorA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4887 (cluster) 4264284 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Trauchessec M., Jaquinod M., Bonvalot A., Brun V., Bruley C., Ropers D., de Jong H., Garin J., Bestel-Corre G., Ferro M., 2014, Mass spectrometry-based workflow for accurate quantification of Escherichia coli enzymes: how proteomics can play a key role in metabolic engineering., Mol Cell Proteomics 13(4):954-68

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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