Gene
Name:	menC
Synonym(s):	ECK2255, EG11532, b2261
Genome position(nucleotides):	2375000 <-- 2375962 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	58.98
External database links:

ASAP:	ABE-0007473
CGSC:	518
ECHOBASE:	EB1494
ECOLIHUB:	menC
OU-MICROARRAY:	b2261
STRING:	511145.b2261
COLOMBOS:	menC

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	pmrDp4	2373566	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.963. P-value: 1.086e-5 Read more >	[ICWHO]	[1]
promoter	pmrDp3	2373574	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 3.814. P-value: 5.119e-5 Read more >	[ICWHO]	[1]
promoter	menBp	2376887	reverse	nd	[AIPP], [ICWHO]	[1], [2]
promoter	TSS_2519 (cluster)	2376914	reverse	For this promoter, there is a cluster of 3 transcription start sites,in the interval 2376912 to 2376914, where the highest frequency is at position 2374936. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[3]

Evidence
[ICWHO] Inferred computationally without human oversight
[AIPP] Automated inference of promoter position
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78
[2] Sharma V., Suvarna K., Meganathan R., Hudspeth ME., 1992, Menaquinone (vitamin K2) biosynthesis: nucleotide sequence and expression of the menB gene from Escherichia coli., J Bacteriol 174(15):5057-62
[3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.