RegulonDB RegulonDB 10.10: Gene Form
   

gdx gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ampC blc gdx ecnB Cis-reg anti-anti-terminator anti-terminator terminator terminator blcp blcp TSS_4966 TSS_4966 sugEp sugEp

Gene      
Name: gdx    Texpresso search in the literature
Synonym(s): ECK4144, EG11616, b4148, sugE
Genome position(nucleotides): 4376875 --> 4377192 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.14
Reference(s): [1] Greener T., et al., 1993
External database links:  
ASAP:
ABE-0013588
CGSC:
34460
ECHOBASE:
EB1573
ECOLIHUB:
sugE
OU-MICROARRAY:
b4148
STRING:
511145.b4148
COLOMBOS: gdx


Product      
Name: guanidinium exporter
Synonym(s): Gdx, SugE
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 10.9
Isoelectric point: 10.321
Motif(s):
 
Type Positions Sequence
29 -> 49 LTPSVITVTAMIVSMALLAWA
58 -> 78 AYAVWTGIGAVGAAITGIVLL
82 -> 102 ANPMRLASLALIVLGIIGLKL
1 -> 21 MSWIILVIAGLLEVVWAVGLK

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
GO:0015299 - solute:proton antiporter activity
biological_process GO:1990961 - xenobiotic detoxification by transmembrane export across the plasma membrane
GO:0006811 - ion transport
GO:0055085 - transmembrane transport
GO:1902600 - proton transmembrane transport
External database links:  
ECOCYC:
SUGE-MONOMER
ECOLIWIKI:
b4148
INTERPRO:
IPR000390
MODBASE:
P69937
PANTHER:
PTHR30561
PFAM:
PF00893
PRIDE:
P69937
PRODB:
PRO_000024011
REFSEQ:
NP_418572
SMR:
P69937
UNIPROT:
P69937


Operon      
Name: gdx         
Operon arrangement:
Transcription unit        Promoter
sugE


RNA cis-regulatory element    
Attenuation: Transcriptional
   
Cis-reg mini-ykkC RNA motif
   
   


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4966 4376799 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Greener T., Govezensky D., Zamir A., 1993, A novel multicopy suppressor of a groEL mutation includes two nested open reading frames transcribed from different promoters., EMBO J 12(3):889-96

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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