RegulonDB RegulonDB 11.1: Gene Form
   

artJ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

rlmC artJ artM ArgR ArgR anti-anti-terminator anti-terminator terminator artJp artJp TSS_1002 (cluster) TSS_1002 (cluster) TSS_1001 TSS_1001

Gene      
Name: artJ    Texpresso search in the literature
Synonym(s): ECK0851, EG11628, b0860
Genome position(nucleotides): 899844 <-- 900575
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 44.81
External database links:  
ASAP:
 ABE-0002927
CGSC:
 31664
ECHOBASE:
 EB1585
ECOLIHUB:
 artJ
OU-MICROARRAY:
 b0860
STRING:
 511145.b0860
COLOMBOS: artJ


Product      
Name: L-arginine ABC transporter periplasmic binding protein
Synonym(s): ArtJ
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,periplasmic space
Molecular weight: 26.829
Isoelectric point: 7.497
Motif(s):
 
Type Positions Sequence Comment
1 -> 19 MKKLVLAALLASFTFGASA
20 -> 243 AEKINFGVSATYPPFESIGANNEIVGFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRKYDAVISGMDITPERSKQVSFTTPYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAFIDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLEKLNNALAAIKADGTYQKISDQWFPQ UniProt: ABC transporter arginine-binding protein 1.
23 -> 242 INFGVSATYPPFESIGANNEIVGFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRKYDAVISGMDITPERSKQVSFTTPYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAFIDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLEKLNNALAAIKADGTYQKISDQWFP
128 -> 128 R UniProt: In Ref. 1; CAA60105..

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.3 - arginine
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.p - ABC superfamily, periplasmic binding component
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0042597 - periplasmic space
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
molecular_function GO:0016597 - amino acid binding
GO:0034618 - arginine binding
GO:0015276 - ligand-gated ion channel activity
biological_process GO:0097638 - L-arginine import across plasma membrane
GO:0006865 - amino acid transport
GO:0071705 - nitrogen compound transport
GO:1903826 - L-arginine transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P30860
ECOCYC:
 ARTJ-MONOMER
ECOLIWIKI:
 b0860
INTERPRO:
 IPR005768
INTERPRO:
 IPR018313
INTERPRO:
 IPR001638
INTERPRO:
 IPR001320
MODBASE:
 P30860
PFAM:
 PF00497
PRIDE:
 P30860
PRODB:
 PRO_000022157
PROSITE:
 PS01039
REFSEQ:
 NP_415381
SMART:
 SM00079
SMART:
 SM00062
SMR:
 P30860
UNIPROT:
 P30860


Operon      
Name: artJ         
Operon arrangement:
Transcription unit        Promoter
artJ


Transcriptional Regulation      
Display Regulation             
Repressed by: ArgR


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1001 900345 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_1002 (cluster) 900605 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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