RegulonDB RegulonDB 11.1: Gene Form
   

uidB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

uidA uidB uidC uidR UidR CRP UxuR uidAp uidAp uidCp6 uidCp6 uidCp5 uidCp5

Gene      
Name: uidB    Texpresso search in the literature
Synonym(s): ECK1611, EG11658, b1616, gusB, uidP
Genome position(nucleotides): 1692890 <-- 1694263
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.82
External database links:  
ASAP:
 ABE-0005407
ECHOBASE:
 EB1610
ECOLIHUB:
 uidB
OU-MICROARRAY:
 b1616
STRING:
 511145.b1616
COLOMBOS: uidB


Product      
Name: glucuronide:H+ symporter
Synonym(s): GusB, UidB, UidP, glucuronide GPH transporter
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 49.908
Isoelectric point: 9.224
Motif(s):
 
Type Positions Sequence Comment
12 -> 34 GYSLGDVANNFAFAMGALFLLSY UniProt: Helical.
38 -> 60 VAGVGAAAAGTMLLLVRVFDAFA UniProt: Helical.
80 -> 100 PFLLFGTAPLMIFSVLVFWVL UniProt: Helical.
109 -> 129 VVYAYLTYMGLGLCYSLVNIP UniProt: Helical.
147 -> 167 LGAARGIAASLTFVCLAFLIG UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015293 - symporter activity
GO:0022857 - transmembrane transporter activity
biological_process GO:0008643 - carbohydrate transport
GO:0006814 - sodium ion transport
GO:0055085 - transmembrane transport
GO:0071702 - organic substance transport
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P0CE44
ECOCYC:
 UIDB-MONOMER
ECOLIWIKI:
 b1616
INTERPRO:
 IPR039672
INTERPRO:
 IPR036259
INTERPRO:
 IPR018043
INTERPRO:
 IPR001927
MODBASE:
 P30868
PANTHER:
 PTHR11328
PFAM:
 PF13347
PRIDE:
 P0CE44
PRODB:
 PRO_000024172
PROSITE:
 PS00872
REFSEQ:
 NP_416133
UNIPROT:
 P0CE44


Operon      
Name: uidABC         
Operon arrangement:
Transcription unit        Promoter
uidABC


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: UidR, UxuR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter uidCp5 1692988 reverse nd [COMP-AINF] [1]
  promoter uidCp6 1693006 reverse nd [COMP-AINF] [1]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

RegulonDB