RegulonDB RegulonDB 11.1: Gene Form
   

cbrA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

dgoT yidR dgoD cbrA dgoA terminator terminator yidRp2 yidRp2 cbrAp6 cbrAp6

Gene      
Name: cbrA    Texpresso search in the literature
Synonym(s): ECK3682, EG11714, b3690, yidS
Genome position(nucleotides): 3869377 --> 3870441
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.46
External database links:  
ASAP:
 ABE-0012068
ECHOBASE:
 EB1665
ECOLIHUB:
 cbrA
OU-MICROARRAY:
 b3690
STRING:
 511145.b3690
COLOMBOS: cbrA


Product      
Name: colicin M resistance protein
Synonym(s): CbrA, YidS
Sequence: Get amino acid sequence Fasta Format
Cellular location: periplasmic space
Molecular weight: 40.142
Isoelectric point: 9.94
Motif(s):
 
Type Positions Sequence Comment
135 -> 168 VIFRADGWEQHITARYLVGADGANSMVRRHLYPD

 
Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.6 - protection
  8 - extrachromosomal --> 8.4 - colicin related
Gene Ontology Terms (GO)  
cellular_component GO:0030288 - outer membrane-bounded periplasmic space
molecular_function GO:0050660 - flavin adenine dinucleotide binding
GO:0071949 - FAD binding
biological_process GO:0030153 - bacteriocin immunity
Note(s): Note(s): ...[more].
Evidence: [EXP-IMP] Inferred from mutant phenotype
Reference(s): [1] Helbig S., et al., 2012
External database links:  
ALPHAFOLD:
 P31456
DIP:
 DIP-12455N
ECOCYC:
 EG11714-MONOMER
ECOLIWIKI:
 b3690
INTERPRO:
 IPR002938
INTERPRO:
 IPR036188
MODBASE:
 P31456
PFAM:
 PF01494
PRIDE:
 P31456
PRODB:
 PRO_000022252
REFSEQ:
 NP_418145
UNIPROT:
 P31456


Operon      
Name: cbrA         
Operon arrangement:
Transcription unit        Promoter
cbrA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter cbrAp6 3869314 forward nd [COMP-AINF] [2]
  promoter yidRp2 3869412 reverse nd [COMP-AINF] [2]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Helbig S., Hantke K., Ammelburg M., Braun V., 2012, CbrA is a flavin adenine dinucleotide protein that modifies the Escherichia coli outer membrane and confers specific resistance to Colicin M., J Bacteriol 194(18):4894-903

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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