RegulonDB RegulonDB 10.9: Gene Form
   

nnr gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

nnr amiB queG tsaE yjeV mutLp1 mutLp1 mutLp2 mutLp2 TSS_5011 TSS_5011 TSS_5010 TSS_5010 queGp queGp yjeFp3 yjeFp3 yjeFp2 yjeFp2 yjeFp1 yjeFp1

Gene      
Name: nnr    Texpresso search in the literature
Synonym(s): ECK4163, EG11758, b4167, yjeF
Genome position(nucleotides): 4394066 --> 4395613 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
57.11
External database links:  
ASAP:
ABE-0013644
ECHOBASE:
EB1708
ECOLIHUB:
yjeF
MIM:
608862
MIM:
615910
OU-MICROARRAY:
b4167
STRING:
511145.b4167
COLOMBOS: nnr


Product      
Name: NAD(P)HX epimerase / NAD(P)HX dehydratase
Synonym(s): Nnr, YjeF
Sequence: Get amino acid sequence Fasta Format
Molecular weight: 54.65
Isoelectric point: 6.427
Motif(s):
 
Type Positions Sequence
139 -> 145 GTGLRQA
258 -> 496 VIIGGDHGTAGAIRMTGEAALRAGAGLVRVLTRSENIAPLLTARPELMVHELTMDSLTESLEWADVVVIGPGLGQQEWGKKALQKVENFRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIESDRLHCAKRLVQRYGGVAVLKGAGTVVAAHPDALGIIDAGNAGMASGGMGDVLSGIIGALLGQKLSPYDAACAGCVAHGAAADVLAARFGTRGMLATDLFSTLQR
432 -> 441 NAGMASGGMG
23 -> 225 IRRGEREAADVLGLTLYELMLRAGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVARLAKAVGIEVTLLAQESDKPLPEEAALAREAWLNAGGEIHASNIVWPESVDLIVDALLGTGLRQAPRESISQLIDHANSHPAPIVAVDIPSGLLAETGATPGAVINADHTITFIALKPGLLTGKARDVTGQLHFDSLGLDSWLAG
412 -> 416 KGAGT

 

Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.6 - protection --> 5.6.2 - detoxification
Gene Ontology Terms (GO)  
molecular_function GO:0003824 - catalytic activity
GO:0005515 - protein binding
GO:0016829 - lyase activity
GO:0016853 - isomerase activity
GO:0046872 - metal ion binding
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0052855 - ADP-dependent NAD(P)H-hydrate dehydratase activity
GO:0052856 - NADHX epimerase activity
GO:0052857 - NADPHX epimerase activity
biological_process GO:0110051 - metabolite repair
GO:0008152 - metabolic process
GO:0046496 - nicotinamide nucleotide metabolic process
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-12572N
ECOCYC:
EG11758-MONOMER
ECOLIWIKI:
b4167
INTERPRO:
IPR029056
INTERPRO:
IPR036652
INTERPRO:
IPR017953
INTERPRO:
IPR004443
INTERPRO:
IPR000631
INTERPRO:
IPR030677
MODBASE:
P31806
PFAM:
PF03853
PFAM:
PF01256
PRIDE:
P31806
PROSITE:
PS51385
PROSITE:
PS51383
PROSITE:
PS01050
PROSITE:
PS01049
REFSEQ:
NP_418588
SMR:
P31806
UNIPROT:
P31806


Operon      
Name: nnr-tsaE-amiB-mutL-miaA-hfq-hflXKC         
Operon arrangement:
Transcription unit        Promoter
yjeFE-amiB-mutL-miaA-hfq-hflXKC
yjeFE-amiB-mutL-miaA-hfq-hflXKC
yjeFE-amiB-mutL-miaA-hfq-hflXKC
mutL-miaA-hfq-hflXKC
mutL-miaA-hfq-hflXKC
miaA-hfq-hflXKC
miaA-hfq-hflXKC
hfq-hflXKC
hfq-hflXKC
hfq-hflXKC
tsaE-amiB-mutL-miaA-hfq-hflXKC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_5010 4395415 forward nd [RS-EPT-CBR] [1]
  promoter TSS_5011 4395713 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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