RegulonDB RegulonDB 10.9: Gene Form
   

ghxP gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yjcE ghxP ryjA soxR terminator anti-terminator anti-anti-terminator anti-anti-terminator anti-terminator terminator TSS_4901 TSS_4901 TSS_4900 (cluster) TSS_4900 (cluster) yjcEp7 yjcEp7 yjcEp8 yjcEp8 yjcDp5 yjcDp5 ghxPp ghxPp yjcDp6 yjcDp6 yjcDp7 yjcDp7 ryjAp ryjAp

Gene      
Name: ghxP    Texpresso search in the literature
Synonym(s): ECK4057, EG11939, b4064, yjcD
Genome position(nucleotides): 4278479 --> 4279828 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
55.93
External database links:  
ASAP:
ABE-0013319
ECHOBASE:
EB1883
ECOLIHUB:
yjcD
OU-MICROARRAY:
b4064
STRING:
511145.b4064
COLOMBOS: ghxP


Product      
Name: guanine/hypoxanthine transporter GhxP
Synonym(s): GhxP, YjcD
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 45.712
Isoelectric point: 6.927
Motif(s):
 
Type Positions Sequence
26 -> 49 RQEVVAGLTTFLAMVYSVIVVPGM
110 -> 129 ALGAVFLMGVLFTVISATGI
60 -> 78 VFVATCLVAGLGSIVMGLW
275 -> 275 T
35 -> 35 T

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
GO:0005345 - purine nucleobase transmembrane transporter activity
GO:0015208 - guanine transmembrane transporter activity
biological_process GO:0098710 - guanine import across plasma membrane
GO:0055085 - transmembrane transport
GO:0006863 - purine nucleobase transport
GO:0035344 - hypoxanthine transport
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-48113N
ECOCYC:
EG11939-MONOMER
ECOLIWIKI:
b4064
INTERPRO:
IPR006043
PFAM:
PF00860
PRIDE:
P0AF52
REFSEQ:
NP_418488
UNIPROT:
P0AF52


Operon      
Name: ghxP         
Operon arrangement:
Transcription unit        Promoter
ghxP


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yjcDp7 4278314 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter yjcDp6 4278318 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter yjcDp5 4278466 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter yjcEp8 4279829 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter yjcEp7 4279835 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter TSS_4900 (cluster) 4279914 forward For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_4901 4279920 forward nd [RS-EPT-CBR] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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