RegulonDB RegulonDB 10.9: Gene Form
   

yjcE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yjcE ghxP yjcF terminator anti-terminator anti-anti-terminator TSS_4901 TSS_4901 TSS_4900 (cluster) TSS_4900 (cluster) yjcEp7 yjcEp7 yjcEp8 yjcEp8

Gene      
Name: yjcE    Texpresso search in the literature
Synonym(s): ECK4058, EG11940, b4065
Genome position(nucleotides): 4279980 --> 4281629 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
55.82
External database links:  
ASAP:
ABE-0013323
ECHOBASE:
EB1884
ECOLIHUB:
yjcE
OU-MICROARRAY:
b4065
STRING:
511145.b4065
COLOMBOS: yjcE


Product      
Name: putative transporter YjcE
Synonym(s): YjcE
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 60.523
Isoelectric point: 5.741
Motif(s):
 
Type Positions Sequence
106 -> 126 WVVPGIPLIPAFALAAVLSPT
50 -> 70 VEFDPELFLVLFIPPLLFADG
187 -> 207 KVAIGGILAGFVVSWLYGRSL
310 -> 330 NVEIWMLFTNIILIYAALMLV
361 -> 381 ILIASFAGVRGAITLAGVLSI

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015297 - antiporter activity
GO:0015299 - solute:proton antiporter activity
GO:0015385 - sodium:proton antiporter activity
GO:0015386 - potassium:proton antiporter activity
biological_process GO:0006811 - ion transport
GO:0006812 - cation transport
GO:0051453 - regulation of intracellular pH
GO:0006814 - sodium ion transport
GO:0055085 - transmembrane transport
GO:0071805 - potassium ion transmembrane transport
GO:1902600 - proton transmembrane transport
GO:0098656 - anion transmembrane transport
GO:0098719 - sodium ion import across plasma membrane
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ECOCYC:
YJCE-MONOMER
ECOLIWIKI:
b4065
INTERPRO:
IPR018422
INTERPRO:
IPR038770
INTERPRO:
IPR006153
INTERPRO:
IPR004705
PANTHER:
PTHR10110
PFAM:
PF00999
PRIDE:
P32703
REFSEQ:
NP_418489
UNIPROT:
P32703


Operon      
Name: yjcE         
Operon arrangement:
Transcription unit        Promoter
yjcE


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yjcEp8 4279829 forward Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter yjcEp7 4279835 forward Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter TSS_4900 (cluster) 4279914 forward For this promoter, there
Read more >
[RS-EPT-CBR] [3]
  promoter TSS_4901 4279920 forward nd [RS-EPT-CBR] [3]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


RegulonDB