Gene
Name:	napF
Synonym(s):	ECK2200, EG12068, b2208, yojG
Genome position(nucleotides):	2303003 <-- 2303497
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	55.35
External database links:

ASAP:	ABE-0007293
CGSC:	36544
ECHOBASE:	EB1995
ECOLIHUB:	napF
OU-MICROARRAY:	b2208
STRING:	511145.b2208
COLOMBOS:	napF

Transcriptional Regulation
	Display Regulation
Activated by:	FNR, FlhDC, NarP, ModE
Repressed by:	IscR, NarL, NarP

Reference(s)
[1] Brondijk TH., Fiegen D., Richardson DJ., Cole JA., 2002, Roles of NapF, NapG and NapH, subunits of the Escherichia coli periplasmic nitrate reductase, in ubiquinol oxidation., Mol Microbiol 44(1):245-55
[2] Giel JL., Rodionov D., Liu M., Blattner FR., Kiley PJ., 2006, IscR-dependent gene expression links iron-sulphur cluster assembly to the control of O-regulated genes in Escherichia coli., Mol Microbiol 60(4):1058-75
[3] Kurata T., Katayama A., Hiramatsu M., Kiguchi Y., Takeuchi M., Watanabe T., Ogasawara H., Ishihama A., Yamamoto K., 2013, Identification of the set of genes, including nonannotated morA, under the direct control of ModE in Escherichia coli., J Bacteriol 195(19):4496-505
[4] Lin AV., Stewart V., 2010, Functional roles for the GerE-family carboxyl-terminal domains of nitrate response regulators NarL and NarP of Escherichia coli K-12., Microbiology 156(Pt 10):2933-43
[5] McNicholas PM., Gunsalus RP., 2002, The molybdate-responsive Escherichia coli ModE transcriptional regulator coordinates periplasmic nitrate reductase (napFDAGHBC) operon expression with nitrate and molybdate availability., J Bacteriol 184(12):3253-9
[6] Nesbit AD., Giel JL., Rose JC., Kiley PJ., 2009, Sequence-specific binding to a subset of IscR-regulated promoters does not require IscR Fe-S cluster ligation., J Mol Biol 387(1):28-41
[7] Stewart V., Bledsoe PJ., 2003, Synthetic lac operator substitutions for studying the nitrate- and nitrite-responsive NarX-NarL and NarQ-NarP two-component regulatory systems of Escherichia coli K-12., J Bacteriol 185(7):2104-11
[8] Stewart V., Bledsoe PJ., Chen LL., Cai A., 2009, Catabolite repression control of napF (periplasmic nitrate reductase) operon expression in Escherichia coli K-12., J Bacteriol 191(3):996-1005
[9] Stewart V., Bledsoe PJ., Williams SB., 2003, Dual overlapping promoters control napF (periplasmic nitrate reductase) operon expression in Escherichia coli K-12., J Bacteriol 185(19):5862-70
[10] Stewart V., Lu Y., Darwin AJ., 2002, Periplasmic nitrate reductase (NapABC enzyme) supports anaerobic respiration by Escherichia coli K-12., J Bacteriol 184(5):1314-23
[11] Wang H., Tseng CP., Gunsalus RP., 1999, The napF and narG nitrate reductase operons in Escherichia coli are differentially expressed in response to submicromolar concentrations of nitrate but not nitrite., J Bacteriol 181(17):5303-8