RegulonDB RegulonDB 10.9: Gene Form
   

mqo gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

mqo yojI eco terminator mqop1 mqop1 mqop5 mqop5 mqop8 mqop8

Gene      
Name: mqo    Texpresso search in the literature
Synonym(s): ECK2202, EG12069, b2210, yojH
Genome position(nucleotides): 2305108 <-- 2306754 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
54.04
Reference(s): [1] van der Rest ME., et al., 2000
External database links:  
ASAP:
ABE-0007300
ECHOBASE:
EB1996
ECOLIHUB:
mqo
OU-MICROARRAY:
b2210
STRING:
511145.b2210
COLOMBOS: mqo


Product      
Name: malate:quinone oxidoreductase
Synonym(s): Mqo, YojH
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,inner membrane
Molecular weight: 60.23
Isoelectric point: 6.985
Motif(s):
 
Type Positions Sequence
31 -> 518 ETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGL

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009898 - cytoplasmic side of plasma membrane
molecular_function GO:0016491 - oxidoreductase activity
GO:0050660 - flavin adenine dinucleotide binding
GO:0008924 - malate dehydrogenase (quinone) activity
GO:0052589 - malate dehydrogenase (menaquinone) activity
biological_process GO:0006099 - tricarboxylic acid cycle
GO:0055114 - oxidation-reduction process
Note(s): Note(s): ...[more].
Reference(s): [2] Kather B., et al., 2000
[3] Nishino K., et al., 2001
[4] Swartz TH., et al., 2005
External database links:  
ECOCYC:
EG12069-MONOMER
ECOLIWIKI:
b2210
INTERPRO:
IPR006231
INTERPRO:
IPR036188
MODBASE:
P33940
PFAM:
PF06039
PRIDE:
P33940
PRODB:
PRO_000023280
REFSEQ:
NP_416714
UNIPROT:
P33940


Operon      
Name: mqo         
Operon arrangement:
Transcription unit        Promoter
mqo


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter mqop8 2306846 reverse Similarity to the consensus
Read more >
[ICWHO] [5]
  promoter mqop5 2306858 reverse Similarity to the consensus
Read more >
[ICWHO] [5]
  promoter mqop1 2306924 reverse Similarity to the consensus
Read more >
[ICWHO] [5]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] van der Rest ME., Frank C., Molenaar D., 2000, Functions of the membrane-associated and cytoplasmic malate dehydrogenases in the citric acid cycle of Escherichia coli., J Bacteriol 182(24):6892-9

 [2] Kather B., Stingl K., van der Rest ME., Altendorf K., Molenaar D., 2000, Another unusual type of citric acid cycle enzyme in Helicobacter pylori: the malate:quinone oxidoreductase., J Bacteriol 182(11):3204-9

 [3] Nishino K., Yamaguchi A., 2001, Analysis of a complete library of putative drug transporter genes in Escherichia coli., J Bacteriol 183(20):5803-12

 [4] Swartz TH., Ito M., Hicks DB., Nuqui M., Guffanti AA., Krulwich TA., 2005, The Mrp Na+/H+ antiporter increases the activity of the malate:quinone oxidoreductase of an Escherichia coli respiratory mutant., J Bacteriol 187(1):388-91

 [5] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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