RegulonDB RegulonDB 10.10: Gene Form
   

sgbE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

sgbU yiaT sgbE sgbH ysaD ysaC lyxK

Gene      
Name: sgbE    Texpresso search in the literature
Synonym(s): ECK3572, EG12287, b3583, yiaS
Genome position(nucleotides): 3750086 --> 3750781 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 57.33
Reference(s): [1] Ibanez E., et al., 2000
External database links:  
ASAP:
 ABE-0011702
ECHOBASE:
 EB2195
ECOLIHUB:
 sgbE
OU-MICROARRAY:
 b3583
STRING:
 511145.b3583
COLOMBOS: sgbE


Product      
Name: L-ribulose-5-phosphate 4-epimerase SgbE
Synonym(s): SgbE, YiaS
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 25.561
Isoelectric point: 5.893
Motif(s):
 
Type Positions Sequence
27 -> 28 GN
74 -> 75 SS
8 -> 196 DVLAANLALPAHHLVTFTWGNVSAVDETRQWMVIKPSGVEYDVMTADDMVVVEIASGKVVEGSKKPSSDTPTHLALYRRYAEIGGIVHTHSRHATIWSQAGLDLPAWGTTHADYFYGAIPCTRQMTAEEINGEYEYQTGEVIIETFEERGRSPAQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYM
44 -> 45 SG

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016853 - isomerase activity
GO:0046872 - metal ion binding
GO:0016832 - aldehyde-lyase activity
GO:0008270 - zinc ion binding
GO:0008742 - L-ribulose-phosphate 4-epimerase activity
biological_process GO:0005975 - carbohydrate metabolic process
GO:0019323 - pentose catabolic process
GO:0019324 - L-lyxose metabolic process
GO:0019572 - L-arabinose catabolic process
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
 EG12287-MONOMER
ECOLIWIKI:
 b3583
INTERPRO:
 IPR004661
INTERPRO:
 IPR036409
INTERPRO:
 IPR001303
MODBASE:
 P37680
PFAM:
 PF00596
PRIDE:
 P37680
PRODB:
 PRO_000023943
REFSEQ:
 NP_418040
SMART:
 SM01007
SMR:
 P37680
SWISSMODEL:
 P37680
UNIPROT:
 P37680


Operon      
Name: yiaKLMNO-lyxK-sgbHUE         
Operon arrangement:
Transcription unit        Promoter
yiaKLMNO-lyx-sgbHUE
yiaKLMNO-lyx-sgbHUE


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, IHF
Repressed by: PlaR
Undetermined regulation CRP


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Ibanez E., Gimenez R., Pedraza T., Baldoma L., Aguilar J., Badia J., 2000, Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose., J Bacteriol 182(16):4625-7

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