RegulonDB

Gene
Name:	sfmF
Synonym(s):	ECK0527, EG12388, b0534, ybcG
Genome position(nucleotides):	563330 --> 563845
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	50.0
External database links:

ASAP:	ABE-0001834
ECHOBASE:	EB2289
ECOLIHUB:	sfmF
OU-MICROARRAY:	b0534
STRING:	511145.b0534
COLOMBOS:	sfmF

Product

Name:

putative fimbrial protein SfmF

Synonym(s):

SfmF, YbcG

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

extracellular space,pilus

Molecular weight:

18.223

Isoelectric point:

4.355

Motif(s):

Type	Positions	Sequence	Comment
	1 -> 20	MRRVLFSCFCGLLWSSSGWA
	21 -> 171	VDPLGTININLHGNVVDFSCTVNTADIDKTVDLGRWPTTQLLNAGDTTALVPFSLRLEGCPPGSVAILFTGTPASDTNLLALDDPAMAQTVAIELRNSDRSRLALGEASPTEEVDANGNVTLNFFANYRALASGVRPGVAKADAIFMINYN	UniProt: Uncharacterized fimbrial-like protein SfmF.
	30 -> 170	NLHGNVVDFSCTVNTADIDKTVDLGRWPTTQLLNAGDTTALVPFSLRLEGCPPGSVAILFTGTPASDTNLLALDDPAMAQTVAIELRNSDRSRLALGEASPTEEVDANGNVTLNFFANYRALASGVRPGVAKADAIFMINY

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		6 - cell structure --> 6.5 - pilus
Gene Ontology Terms (GO)
	cellular_component	GO:0009289 - pilus GO:0005576 - extracellular region
	biological_process	GO:0007155 - cell adhesion GO:0043709 - cell adhesion involved in single-species biofilm formation

Note(s):

Note(s): ...[more].

Evidence:

[COMP-HINF-FN-FROM-SEQ] Human inference of function from sequence
[EXP-IMP] Inferred from mutant phenotype

Reference(s):

[1] Korea CG., et al., 2010
[2] Korea CG., et al., 2011
[3] Wurpel DJ., et al., 2013

External database links:

ALPHAFOLD:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PFAM:

PRIDE:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

sfmHF

Operon arrangement:

Transcription unit	Promoter
sfmHF

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_681	564377		forward	nd	[RS-EPT-CBR]	[4]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Korea CG., Badouraly R., Prevost MC., Ghigo JM., Beloin C., 2010, Escherichia coli K-12 possesses multiple cryptic but functional chaperone-usher fimbriae with distinct surface specificities., Environ Microbiol 12(7):1957-77
[2] Korea CG., Ghigo JM., Beloin C., 2011, The sweet connection: Solving the riddle of multiple sugar-binding fimbrial adhesins in Escherichia coli: Multiple E. coli fimbriae form a versatile arsenal of sugar-binding lectins potentially involved in surface-colonisation and tissue tropism., Bioessays 33(4):300-11
[3] Wurpel DJ., Beatson SA., Totsika M., Petty NK., Schembri MA., 2013, Chaperone-usher fimbriae of Escherichia coli., PLoS One 8(1):e52835
[4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.