RegulonDB RegulonDB 11.1: Gene Form
   

gatC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gatC gatD gatB TSS_2410 TSS_2410 TSS_2409 (cluster) TSS_2409 (cluster) TSS_2408 TSS_2408 TSS_2407 TSS_2407 TSS_2406 (cluster) TSS_2406 (cluster)

Gene      
Name: gatC    Texpresso search in the literature
Synonym(s): ECK2085, EG12416, b2092
Type: Pseudo Gene
Genome position(nucleotides): 2172921 <-- 2174278
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.25
External database links:  
ASAP:
 ABE-0006928
ECHOBASE:
 EB2315
ECOLIHUB:
 gatC
OU-MICROARRAY:
 b2092
STRING:
 511145.b2092
UNIPROT:
 P69831
COLOMBOS: gatC


Product      
Name: galactitol-specific PTS enzyme IIC component
Sequence: Get amino acid sequence Fasta Format
Isoelectric point: 10.613
Motif(s):
 
Type Positions Sequence Comment
9 -> 29 ILDLGPTVMLPIVIIIFSKIL UniProt: Helical.
41 -> 61 LHIGIGFVGIGLVIGLMLDSI UniProt: Helical.
92 -> 112 ASQIALVAIPIAILVNVAMLL UniProt: Helical.
138 -> 158 LATGSWMIGMAGVVIHAAFVY UniProt: Helical.
187 -> 203 MGPIAVLVDAIIEKIPG UniProt: (in Ref. 1; CAA56230).

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
  4 - transport --> 4.4 - Group Translocators --> 4.4.A - Phosphotransferase Systems (PEP-dependent PTS)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
GO:1902495 - transmembrane transporter complex
molecular_function GO:0005515 - protein binding
GO:0015577 - galactitol transmembrane transporter activity
GO:0090584 - protein-phosphocysteine-galactitol-phosphotransferase system transporter activity
biological_process GO:0008643 - carbohydrate transport
GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0019402 - galactitol metabolic process
GO:0015796 - galactitol transport
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P69831
ECOCYC:
 GATC-MONOMER
ECOLIWIKI:
 b2092
INTERPRO:
 IPR013014
INTERPRO:
 IPR004703
INTERPRO:
 IPR013853
PANTHER:
 PTHR37324
PFAM:
 PF03611
PRIDE:
 P69831
PRODB:
 PRO_000022755
PROSITE:
 PS51104
REFSEQ:
 NP_416595
SMR:
 P69831
UNIPROT:
 P69831


Operon      
Name: gatYZABCD         
Operon arrangement:
Transcription unit        Promoter
gatZABCD
gatYZABCD


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: ArcA, GatR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2406 (cluster) 2172607 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2407 2174427 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2408 2174431 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2409 (cluster) 2174473 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2410 2174500 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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