RegulonDB RegulonDB 11.1: Gene Form
   

proL gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

lapC insH8 b2191 proL Fis yejOp yejOp proLp proLp TSS_2482 (cluster) TSS_2482 (cluster)

Gene      
Name: proL    Texpresso search in the literature
Synonym(s): ECK2183, EG30067, b2189, proW
Genome position(nucleotides): 2286211 --> 2286287
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 66.23
External database links:  
ASAP:
 ABE-0007242
CGSC:
 17629
ECHOBASE:
 EB4230
ECOLIHUB:
 proL
OU-MICROARRAY:
 b2189
COLOMBOS: proL


Product      
Name: tRNA-Pro(GGG)
Synonym(s): tRNAproL
Type: tRNAs
Cellular location: cytosol
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.2 - RNA related --> 2.2.5 - tRNA
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0030533 - triplet codon-amino acid adaptor activity
Note(s): Note(s): ...[more].
Evidence: [AS-TAS] Traceable author statement
Reference(s): [1] Mohanty BK., et al., 2016
[2] Siekevitz P., et al., 1981
External database links:  
ECOCYC:
 proL-tRNA
ECOLIWIKI:
 b2189


Operon      
Name: proL         
Operon arrangement:
Transcription unit        Promoter
proL


Transcriptional Regulation      
Display Regulation             
Activated by: Fis


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2482 (cluster) 2285798 forward nd [RS-EPT-CBR] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Mohanty BK., Petree JR., Kushner SR., 2016, Endonucleolytic cleavages by RNase E generate the mature 3' termini of the three proline tRNAs in Escherichia coli., Nucleic Acids Res 44(13):6350-62

 [2] Siekevitz P., Zamecnik PC., 1981, Ribosomes and protein synthesis., J Cell Biol 91(3 Pt 2):53s-65s

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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