RegulonDB RegulonDB 10.9: Gene Form
   

sibC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

serA fau sibC ibsC SibC TSS_3200 TSS_3200 TSS_3199 TSS_3199 TSS_3198 TSS_3198 TSS_3197 TSS_3197 TSS_3196 TSS_3196 TSS_3195 TSS_3195 TSS_3194 TSS_3194 TSS_3193 TSS_3193 sibCp sibCp

Gene      
Name: sibC    Texpresso search in the literature
Synonym(s): ECK2908, G0-8886, QUAD1c, b4446, rygC, t27
Genome position(nucleotides): 3056851 --> 3056991 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
47.52
External database links:  
ASAP:
ABE-0047266
ECHOBASE:
EB4532
ECOLIHUB:
sibC
COLOMBOS: sibC


Product      
Name: small regulatory RNA antitoxin SibC
Synonym(s): QUAD1c, RygC, SibC, T27
Type: small RNA
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.2 - RNA related --> 2.2.7 - antisense RNA
Gene Ontology Terms (GO)  
biological_process GO:0035194 - post-transcriptional gene silencing by RNA
Note(s): Note(s): ...[more].
Evidence: [IMP] Inferred from mutant phenotype
Reference(s): [1] Fozo EM., et al., 2008
[2] Peano C., et al., 2015
External database links:  
ECOCYC:
RYGC-RNA
ECOLIWIKI:
b4446


Operon      
Name: sibC         
Operon arrangement:
Transcription unit        Promoter
sibC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3193 3057340 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3194 3057467 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3195 3057593 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3196 3057726 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3197 3057734 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3198 3058242 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3199 3058303 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3200 3058379 reverse nd [RS-EPT-CBR] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Fozo EM., Kawano M., Fontaine F., Kaya Y., Mendieta KS., Jones KL., Ocampo A., Rudd KE., Storz G., 2008, Repression of small toxic protein synthesis by the Sib and OhsC small RNAs., Mol Microbiol 70(5):1076-93

 [2] Peano C., Wolf J., Demol J., Rossi E., Petiti L., De Bellis G., Geiselmann J., Egli T., Lacour S., Landini P., 2015, Characterization of the Escherichia coli σ(S) core regulon by Chromatin Immunoprecipitation-sequencing (ChIP-seq) analysis., Sci Rep 5:10469

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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