RegulonDB RegulonDB 11.1: Gene Form
   

flgD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

flgE flgD flgC TSS_1345 TSS_1345 TSS_1344 TSS_1344

Gene      
Name: flgD    Texpresso search in the literature
Synonym(s): ECK1060, G360, b1075, flaV
Genome position(nucleotides): 1131854 --> 1132549
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.6
External database links:  
ASAP:
 ABE-0003645
CGSC:
 755
ECHOBASE:
 EB4016
ECOLIHUB:
 flgD
OU-MICROARRAY:
 b1075
STRING:
 511145.b1075
COLOMBOS: flgD


Product      
Name: flagellar biosynthesis, initiation of hook assembly
Synonym(s): FlaV, FlgD
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 23.575
Isoelectric point: 3.961
Motif(s):
 
Type Positions Sequence Comment
1 -> 26 MSIAVTTTDPTNTGVSTTSSSSLTGS UniProt: Disordered; Sequence Annotation Type: region of interest.
7 -> 78 TTDPTNTGVSTTSSSSLTGSNAADLQSSFLTLLVAQLKNQDPTNPMENNELTSQLAQISTVSGIEKLNTTLG
87 -> 228 SQSLQASNLIGHGVMIPGTTVLAGTGSEEGAVTTTTPFGVELQQAADKVTATITDKNGAVVRTIDIGELTAGVHSFTWDGTLTDGSTAPNGSYNVAISASNGGTQLVAQPLQFALVQGVIRGNSGNTLDLGTYGTTTLDEVR
119 -> 188 TTTTPFGVELQQAADKVTATITDKNGAVVRTIDIGELTAGVHSFTWDGTLTDGSTAPNGSYNVAISASNG

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.12 - flagellum
  5 - cell processes --> 5.3 - motility, chemotaxis, energytaxis (aerotaxis, redoxtaxis etc)
  6 - cell structure --> 6.4 - flagella
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
biological_process GO:0071978 - bacterial-type flagellum-dependent swarming motility
GO:0044781 - bacterial-type flagellum organization
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P75936
DIP:
 DIP-9632N
ECOCYC:
 G360-MONOMER
ECOLIWIKI:
 b1075
INTERPRO:
 IPR025963
INTERPRO:
 IPR025965
INTERPRO:
 IPR005648
PFAM:
 PF13860
PFAM:
 PF03963
PFAM:
 PF13861
PRIDE:
 P75936
PRODB:
 PRO_000022640
REFSEQ:
 NP_415593
SMR:
 P75936
UNIPROT:
 P75936


Operon      
Name: flgBCDEFGHIJ         
Operon arrangement:
Transcription unit        Promoter
flgBCDEFGHIJ


Transcriptional Regulation      
Display Regulation             
Activated by: FlhDC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1344 1131956 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1345 1132384 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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