RegulonDB

Gene
Name:	qmcA
Synonym(s):	ECK0483, G6265, b0489, ybbK
Genome position(nucleotides):	514856 <-- 515773 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	52.83
External database links:

ASAP:	ABE-0001697
ECHOBASE:	EB3046
ECOLIHUB:	qmcA
OU-MICROARRAY:	b0489
STRING:	511145.b0489
COLOMBOS:	qmcA

Product

Name:

PHB domain-containing protein QmcA

Synonym(s):

QmcA, YbbK

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol,inner membrane

Molecular weight:

33.743

Isoelectric point:

5.296

Motif(s):

Type	Positions	Sequence
	238 -> 297	MVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKD
	3 -> 23	IFIPILIFVALVIVGAGVKIV
	22 -> 202	IVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIRDVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEG

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)
	cellular_component	GO:0005829 - cytosol GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane
	molecular_function	GO:0005515 - protein binding GO:0042802 - identical protein binding

Note(s):

Note(s): ...[more].

Reference(s):

[1] Hinderhofer M., et al., 2009
[2] Padilla-Vaca F., et al., 2019

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

PFAM:

PFAM:

PRIDE:

PRINTS:

PRODB:

PROSITE:

REFSEQ:

SMART:

UNIPROT:

Operon

Name:

qmcA-ybbJ

Operon arrangement:

Transcription unit	Promoter
qmcA-ybbJ	qmcAp

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	ybbJp1	515077	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 8.269. P-value: 2.194e-6 Read more >	[ICWHO]	[3]
promoter	TSS_659 (cluster)	515825	reverse	For this promoter, there is a cluster of 2 transcription start sites,in the interval 515824 to 515825, where the highest frequency is at position 515049. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[4]
promoter	ybbLp6	515892	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.336. P-value: 9.327e-5 Read more >	[ICWHO], [RS-EPT-CBR]	[3], [4]

Evidence
[ICWHO] Inferred computationally without human oversight
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Hinderhofer M., Walker CA., Friemel A., Stuermer CA., Moller HM., Reuter A., 2009, Evolution of prokaryotic SPFH proteins., BMC Evol Biol 9:10
[2] Padilla-Vaca F., Vargas-Maya NI., Elizarraras-Vargas NU., Rangel-Serrano A., Cardoso-Reyes LR., Razo-Soria T., Membrillo-Hernandez J., Franco B., 2019, Flotillin homologue is involved in the swimming behavior of Escherichia coli., Arch Microbiol 201(7):999-1008
[3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78
[4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.