RegulonDB RegulonDB 11.1: Gene Form
   

gfcD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gfcD gfcE gfcC gfcB etp gfcDp3 gfcDp3

Gene      
Name: gfcD    Texpresso search in the literature
Synonym(s): ECK0975, G6505, b0984, ymcA
Genome position(nucleotides): 1045849 <-- 1047945
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.98
External database links:  
ASAP:
 ABE-0003319
ECHOBASE:
 EB3493
ECOLIHUB:
 gfcD
OU-MICROARRAY:
 b0984
STRING:
 511145.b0984
COLOMBOS: gfcD


Product      
Name: putative lipoprotein GfcD
Synonym(s): GfcD, YmcA
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,outer membrane
Molecular weight: 78.687
Isoelectric point: 6.008
Motif(s):
 
Type Positions Sequence Comment
1 -> 18 MKKNSYLLSCLAIAVSSA
19 -> 698 CHAEVLTYPDPLGSSQSDFGGTGLLQMPNARIAPEGEFSVNYRDNDQYRFYSTSVALFPWLEGTIRYTDVRTRKYSQWEDFSGDQSYKDKSFDFKLRLWEEGYWLPQVAFGKRDIAGTGLFDGEYLVASKQAGPFDFTLGMAWGYAGNAGNITNPFCRVSDKYCHRAESHDAGDISFSDIFRGPASIFGGIEYQTPWNPLRLKLEYDGNNYQNDFAGKLPQASHFNVGAVYRAASWADLNLSYERGNTLMFGFTLRTNFNDLRPALRDTPKPAYQPAPESEGLQYTTVANQLTALKYNAGFDAPEIQLRDKTLYMSGQQYKYRDSREAVDRANRILVNNLPQGVEKISVTQKREHMAMVTTETDVASLRKQLAGTAPGQSEPLQQQRVEAEDLSAFGRGYRIREDRFSYSFNPTLSQSLGGPEDFYMFQLGLMSSARYWFTDHLLLDGGIFTNIYNNYDKFKSSLLPADSTLPRVRTHIRDYVRNDVYLNNLQANYFADLGNGFYGQVYGGYLETMYAGVGSELLYRPLDACWALGVDVNYVKQRDWDNMMRFTDYSTPTGFVTAYWNPPTLNGVLMKLSVGQYLAKDKGATIDVAKRFDSGVAVGVWAAISNVSKDDYGEGGFSKGFYISIPFDLMTIGPNRNRAVVSWTPLTRDGGQMLSRKYQLYPMTAEREVPVGQ UniProt: Uncharacterized lipoprotein GfcD.
33 -> 690 SQSDFGGTGLLQMPNARIAPEGEFSVNYRDNDQYRFYSTSVALFPWLEGTIRYTDVRTRKYSQWEDFSGDQSYKDKSFDFKLRLWEEGYWLPQVAFGKRDIAGTGLFDGEYLVASKQAGPFDFTLGMAWGYAGNAGNITNPFCRVSDKYCHRAESHDAGDISFSDIFRGPASIFGGIEYQTPWNPLRLKLEYDGNNYQNDFAGKLPQASHFNVGAVYRAASWADLNLSYERGNTLMFGFTLRTNFNDLRPALRDTPKPAYQPAPESEGLQYTTVANQLTALKYNAGFDAPEIQLRDKTLYMSGQQYKYRDSREAVDRANRILVNNLPQGVEKISVTQKREHMAMVTTETDVASLRKQLAGTAPGQSEPLQQQRVEAEDLSAFGRGYRIREDRFSYSFNPTLSQSLGGPEDFYMFQLGLMSSARYWFTDHLLLDGGIFTNIYNNYDKFKSSLLPADSTLPRVRTHIRDYVRNDVYLNNLQANYFADLGNGFYGQVYGGYLETMYAGVGSELLYRPLDACWALGVDVNYVKQRDWDNMMRFTDYSTPTGFVTAYWNPPTLNGVLMKLSVGQYLAKDKGATIDVAKRFDSGVAVGVWAAISNVSKDDYGEGGFSKGFYISIPFDLMTIGPNRNRAVVSWTPLTRDGGQMLSRKYQLYPMTA

 
Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0009279 - cell outer membrane
GO:0016020 - membrane
GO:0005886 - plasma membrane
Note(s): Note(s): ...[more].
Reference(s): [1] Rao S., et al., 2020
External database links:  
ALPHAFOLD:
 P75882
DIP:
 DIP-12707N
ECOCYC:
 G6505-MONOMER
ECOLIWIKI:
 b0984
INTERPRO:
 IPR010344
PFAM:
 PF06082
PRIDE:
 P75882
PROSITE:
 PS51257
REFSEQ:
 NP_415504
UNIPROT:
 P75882


Operon      
Name: gfcBCD         
Operon arrangement:
Transcription unit        Promoter
gfcBCD


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter gfcDp3 1048118 reverse nd [COMP-AINF] [2]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Rao S., Bates GT., Matthews CR., Newport TD., Vickery ON., Stansfeld PJ., 2020, Characterizing Membrane Association and Periplasmic Transfer of Bacterial Lipoproteins through Molecular Dynamics Simulations., Structure 28(4):475-487.e3

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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