RegulonDB RegulonDB 10.10: Gene Form
   

nagZ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

nagZ thiK ycfP lpoB TSS_1439 TSS_1439 TSS_1438 TSS_1438 TSS_1437 TSS_1437 TSS_1436 TSS_1436

Gene      
Name: nagZ    Texpresso search in the literature
Synonym(s): ECK1093, G6567, b1107, ycfO
Genome position(nucleotides): 1164095 --> 1165120 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 53.02
External database links:  
ASAP:
 ABE-0003737
ECHOBASE:
 EB3207
ECOLIHUB:
 nagZ
OU-MICROARRAY:
 b1107
STRING:
 511145.b1107
COLOMBOS: nagZ


Product      
Name: β-N-acetylhexosaminidase
Synonym(s): NagZ, YcfO, hexosaminidase
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 37.595
Isoelectric point: 6.237
Motif(s):
 
Type Positions Sequence
9 -> 299 EGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNRLVVAVDQEGGRVQRFREGFTRLPAAQSFAALSGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAER
163 -> 164 KH

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.34 - murein turnover, recycling
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0102148 - N-acetyl-beta-D-galactosaminidase activity
GO:0016787 - hydrolase activity
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016798 - hydrolase activity, acting on glycosyl bonds
GO:0004563 - beta-N-acetylhexosaminidase activity
biological_process GO:0008152 - metabolic process
GO:0051301 - cell division
GO:0005975 - carbohydrate metabolic process
GO:0007049 - cell cycle
GO:0009252 - peptidoglycan biosynthetic process
GO:0009254 - peptidoglycan turnover
GO:0008360 - regulation of cell shape
GO:0071555 - cell wall organization
Note(s): Note(s): ...[more].
External database links:  
CAZY:
 GH3
ECOCYC:
 G6567-MONOMER
ECOLIWIKI:
 b1107
INTERPRO:
 IPR022956
INTERPRO:
 IPR036962
INTERPRO:
 IPR001764
INTERPRO:
 IPR017853
INTERPRO:
 IPR019800
MODBASE:
 P75949
PFAM:
 PF00933
PRIDE:
 P75949
PRODB:
 PRO_000023341
PROSITE:
 PS00775
REFSEQ:
 NP_415625
SMR:
 P75949
SWISSMODEL:
 P75949
UNIPROT:
 P75949


Operon      
Name: hinT-ycfL-lpoB-thiK-nagZ-ycfP         
Operon arrangement:
Transcription unit        Promoter
hinT-ycfL-lpoB-thiK-nagZ-ycfP


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1436 1163603 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1437 1164943 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1438 1165016 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1439 1165531 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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