RegulonDB RegulonDB 10.8: Gene Form
   

ompG gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

Gene      
Name: ompG    Texpresso search in the literature
Synonym(s): ECK1315, G6657, b1319
Genome position(nucleotides): 1381947 --> 1382852 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
49.89
External database links:  
ASAP:
ABE-0004425
ECHOBASE:
EB3202
OU-MICROARRAY:
b1319
PortEco:
ompG
STRING:
511145.b1319
COLOMBOS: ompG


Product      
Name: outer membrane porin G
Synonym(s): OmpG
Sequence: Get amino acid sequence Fasta Format
Cellular location: outer membrane
Molecular weight: 34.913
Isoelectric point: 4.215
Motif(s):
 
Type Positions Sequence
90 -> 99 PELEVHYQFL
172 -> 182 VETETGLQYTF
213 -> 222 EIRAYLPLTL
252 -> 252 H
282 -> 282 H

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.1 - Channel-type Transporters --> 4.1.B - Beta barrel porins (The Outer Membrane Porin (OMP) Functional Superfamily)
Gene Ontology Terms (GO)  
cellular_component GO:0009279 - cell outer membrane
GO:0016020 - membrane
GO:0016021 - integral component of membrane
GO:0045203 - integral component of cell outer membrane
GO:0046930 - pore complex
molecular_function GO:0015288 - porin activity
GO:0015478 - oligosaccharide transporting porin activity
GO:0015481 - maltose transporting porin activity
biological_process GO:0006811 - ion transport
GO:0015768 - maltose transport
GO:0015772 - oligosaccharide transport
GO:0034219 - carbohydrate transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Anbazhagan V., et al., 2008
[2] Behlau M., et al., 2001
[3] Conlan S., et al., 2003
[4] Conlan S., et al., 2000
[5] Fajardo DA., et al., 1998
[6] Hiller M., et al., 2005
[7] Korkmaz F., et al., 2008
[8] Koster S., et al., 2015
[9] Misra R., et al., 1989
[10] Thoma J., et al., 2018
External database links:  
DIP:
DIP-10399N
ECOCYC:
G6657-MONOMER
ECOLIWIKI:
b1319
INTERPRO:
IPR018981
MINT:
MINT-1227757
PDB:
2IWW
PDB:
2JQY
PDB:
2WVP
PDB:
2X9K
PDB:
2IWV
PDB:
2F1C
PDB:
4CTD
PDB:
6OQH
PDB:
5MWV
PFAM:
PF09381
PRIDE:
P76045
PRODB:
PRO_000023453
REFSEQ:
NP_415835
SMR:
P76045
UNIPROT:
P76045


Operon      
Name: ycjMNOPQRSTUV-ymjB-ompG         
Operon arrangement:
Transcription unit        Promoter
 


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Anbazhagan V., Qu J., Kleinschmidt JH., Marsh D., 2008, Incorporation of outer membrane protein OmpG in lipid membranes: protein-lipid interactions and beta-barrel orientation., Biochemistry 47(23):6189-98

 [2] Behlau M., Mills DJ., Quader H., Kuhlbrandt W., Vonck J., 2001, Projection structure of the monomeric porin OmpG at 6 A resolution., J Mol Biol 305(1):71-7

 [3] Conlan S., Bayley H., 2003, Folding of a monomeric porin, OmpG, in detergent solution., Biochemistry 42(31):9453-65

 [4] Conlan S., Zhang Y., Cheley S., Bayley H., 2000, Biochemical and biophysical characterization of OmpG: A monomeric porin., Biochemistry 39(39):11845-54

 [5] Fajardo DA., Cheung J., Ito C., Sugawara E., Nikaido H., Misra R., 1998, Biochemistry and regulation of a novel Escherichia coli K-12 porin protein, OmpG, which produces unusually large channels., J Bacteriol 180(17):4452-9

 [6] Hiller M., Krabben L., Vinothkumar KR., Castellani F., van Rossum BJ., Kuhlbrandt W., Oschkinat H., 2005, Solid-state magic-angle spinning NMR of outer-membrane protein G from Escherichia coli., Chembiochem 6(9):1679-84

 [7] Korkmaz F., Koster S., Yildiz O., Mantele W., 2008, The role of lipids for the functional integrity of porin: an FTIR study using lipid and protein reporter groups., Biochemistry 47(46):12126-34

 [8] Koster S., van Pee K., Yildiz O., 2015, Purification, Refolding, and Crystallization of the Outer Membrane Protein OmpG from Escherichia coli., Methods Enzymol 557:149-66

 [9] Misra R., Benson SA., 1989, A novel mutation, cog, which results in production of a new porin protein (OmpG) of Escherichia coli K-12., J Bacteriol 171(8):4105-11

 [10] Thoma J., Manioglu S., Kalbermatter D., Bosshart PD., Fotiadis D., Muller DJ., 2018, Protein-enriched outer membrane vesicles as a native platform for outer membrane protein studies., Commun Biol 1:23


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