RegulonDB RegulonDB 10.9: Gene Form
   

ynfK gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

Gene      
Name: ynfK    Texpresso search in the literature
Synonym(s): ECK1588, G6851, b1593
Genome position(nucleotides): 1666524 <-- 1667219 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
52.16
External database links:  
ASAP:
ABE-0005319
ECHOBASE:
EB3610
ECOLIHUB:
ynfK
OU-MICROARRAY:
b1593
STRING:
511145.b1593
COLOMBOS: ynfK


Product      
Name: putative dethiobiotin synthetase
Synonym(s): YnfK
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 24.981
Isoelectric point: 6.517
Motif(s):
 
Type Positions Sequence
201 -> 203 PYL
4 -> 207 RFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGSKETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANLTEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIANDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAE
13 -> 18 SVGKTV
112 -> 115 EGTG
172 -> 173 NR

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.3 - cofactors, small molecule carriers --> 1.5.3.1 - biotin
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0046872 - metal ion binding
GO:0016874 - ligase activity
GO:0004141 - dethiobiotin synthase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0000287 - magnesium ion binding
biological_process GO:0009102 - biotin biosynthetic process
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
G6851-MONOMER
ECOLIWIKI:
b1593
INTERPRO:
IPR004472
INTERPRO:
IPR027417
MODBASE:
P0A6E9
PANTHER:
PTHR43210
PFAM:
PF13500
PRIDE:
P0A6E9
REFSEQ:
NP_416110
SMR:
P0A6E9
SWISSMODEL:
P0A6E9
UNIPROT:
P0A6E9


Operon      
Name: mlc-ynfK         
Operon arrangement:
Transcription unit        Promoter
mlc-ynfK
mlc-ynfK
mlc
ynfK


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: Mlc


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1876 (cluster) 1667036 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [1]
  promoter ynfKp5 1667240 reverse Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter TSS_1877 1667270 reverse nd [RS-EPT-CBR] [1]
  promoter ynfKp6 1667335 reverse Similarity to the consensus
Read more >
[ICWHO] [2]



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