RegulonDB RegulonDB 11.1: Gene Form
   

drpB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yedJ drpB rseX terminator rseXp rseXp TSS_2277 TSS_2277 yedJp4 yedJp4 yedJp3 yedJp3

Gene      
Name: drpB    Texpresso search in the literature
Synonym(s): ECK1961, G7051, b1963, yedR
Genome position(nucleotides): 2033119 <-- 2033421
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 53.8
External database links:  
ASAP:
 ABE-0006514
ECHOBASE:
 EB3795
ECOLIHUB:
 yedR
OU-MICROARRAY:
 b1963
STRING:
 511145.b1963
COLOMBOS: drpB


Product      
Name: cell division protein DrpB
Synonym(s): DrpB, YedR
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 11.325
Isoelectric point: 9.999
Motif(s):
 
Type Positions Sequence Comment
17 -> 37 GGKLALWAFYTWCGYFVWAMA UniProt: Helical.
65 -> 85 WLGALVGFLFMALVGALLGSI UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.1 - cell division
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
GO:0032153 - cell division site
molecular_function GO:0005515 - protein binding
biological_process GO:0051301 - cell division
GO:0007049 - cell cycle
GO:0043093 - FtsZ-dependent cytokinesis
Note(s): Note(s): ...[more].
Evidence: [EXP-IGI] Inferred from genetic interaction
Reference(s): [1] Yahashiri A., et al., 2020
External database links:  
ALPHAFOLD:
 P76334
DIP:
 DIP-11849N
ECOCYC:
 G7051-MONOMER
ECOLIWIKI:
 b1963
PRIDE:
 P76334
REFSEQ:
 NP_416472
UNIPROT:
 P76334


Operon      
Name: drpB-yedJ         
Operon arrangement:
Transcription unit        Promoter
yedRJ


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yedJp3 2033203 reverse nd [COMP-AINF] [2]
  promoter yedJp4 2033223 reverse nd [COMP-AINF] [2]
  promoter TSS_2277 2033449 reverse nd [RS-EPT-CBR] [3]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Yahashiri A., Babor JT., Anwar AL., Bezy RP., Piette EW., Arends SJR., Muh U., Steffen MR., Cline JM., Stanek DN., Lister SD., Swanson SM., Weiss DS., 2020, DrpB (YedR) Is a Nonessential Cell Division Protein in Escherichia coli., J Bacteriol 202(23)

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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