RegulonDB RegulonDB 11.1: Gene Form
   

wcaL gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

wzxC wcaM wcaK wcaL wcaMp1 wcaMp1

Gene      
Name: wcaL    Texpresso search in the literature
Synonym(s): ECK2038, G7095, b2044, yefL
Genome position(nucleotides): 2115907 <-- 2117127
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.87
External database links:  
ASAP:
 ABE-0006777
ECHOBASE:
 EB2522
ECOLIHUB:
 wcaL
MIM:
 300818
MIM:
 300868
OU-MICROARRAY:
 b2044
STRING:
 511145.b2044
COLOMBOS: wcaL


Product      
Name: putative colanic acid biosynthesis glycosyl transferase WcaL
Synonym(s): WcaL, YefL, orf19
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 45.362
Isoelectric point: 9.531
Motif(s):
 
Type Positions Sequence Comment
15 -> 210 ETFVLNQITAFIDMGFEVEILALQKGDTQNTHAAWTKYNLAARTRWLQDEPTGKVAKLRHRASQTLRGIHRKNTWQALNLKRYGAESRNLILSAICGQVATPFRADVFIAHFGPAGVTAAKLRELGVIRGKIATIFHGIDISSREVLNHYTPEYQQLFRRGDLMLPISDLWAGRLQKMGCPREKIAVSRMGVDMTR
126 -> 126 F UniProt: In Ref. 2; AAC77851..
129 -> 129 A UniProt: In Ref. 2; AAC77851..
144 -> 144 G UniProt: In Ref. 2; AAC77851..
205 -> 205 G UniProt: In Ref. 2; AAC77851..

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.2 - colanic acid (M antigen)
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016757 - glycosyltransferase activity
GO:0016740 - transferase activity
biological_process GO:0009103 - lipopolysaccharide biosynthetic process
GO:0046377 - colanic acid metabolic process
GO:0045228 - slime layer polysaccharide biosynthetic process
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P71243
CAZY:
 GT4
DIP:
 DIP-11127N
ECOCYC:
 G7095-MONOMER
ECOLIWIKI:
 b2044
INTERPRO:
 IPR023884
INTERPRO:
 IPR001296
INTERPRO:
 IPR028098
MODBASE:
 P71243
PFAM:
 PF00534
PFAM:
 PF13439
PRIDE:
 P71243
REFSEQ:
 NP_416548
UNIPROT:
 P71243


Operon      
Name: wcaKLM         
Operon arrangement:
Transcription unit        Promoter
wcaKLM


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter wcaMp1 2115934 reverse nd [COMP-AINF] [1]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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