RegulonDB RegulonDB 10.9: Gene Form
   

wcaK gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

wzxC wcaM wcaK wcaL wcaMp1 wcaMp1

Gene      
Name: wcaK    Texpresso search in the literature
Synonym(s): ECK2039, G7096, b2045
Genome position(nucleotides): 2117124 <-- 2118404 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
54.33
External database links:  
ASAP:
ABE-0006780
ECHOBASE:
EB3347
ECOLIHUB:
wcaK
OU-MICROARRAY:
b2045
STRING:
511145.b2045
COLOMBOS: wcaK


Product      
Name: putative colanic acid biosynthesis pyruvyl transferase WcaK
Synonym(s): WcaK, orf18
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 47.344
Isoelectric point: 7.102
Motif(s):
 
Type Positions Sequence
77 -> 77 K
13 -> 356 NRGDSAILRGLLDAINILNPHAEVDVMSRYPVSSSWLLNRPVMGDPLFLQMKQHNSAAGVVGRVKKVLRRRYQHQVLLSRVTDTGKLRNIAIAQGFTDFVRLLSGYDAIIQVGGSFFVDLYGVPQFEHALCTFMAKKPLFMIGHSVGPFQDEQFNQLANYVFGHCDALILRESVSFDLMKRSNITTAKVEHGVDTAWLVDHHTEDFTASYAVQHWLDVAAQQKTVAITLRELAPFDKRLGTTQQAYEKAFAGVVNRILDEGYQVIALSTCTGIDSYNKDDRMVALNLRQHISDPARYHVVMDELNDLEMGKILGACELTVGTRLHSAIISMNFATPAIAINYEH

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.2 - colanic acid (M antigen)
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016740 - transferase activity
biological_process GO:0009103 - lipopolysaccharide biosynthetic process
GO:0045228 - slime layer polysaccharide biosynthetic process
Note(s): Note(s): ...[more].
Evidence: [IGC] Inferred from genomic context
Reference(s): [1] Stevenson G., et al., 1996
External database links:  
ECOCYC:
G7096-MONOMER
ECOLIWIKI:
b2045
INTERPRO:
IPR023918
INTERPRO:
IPR007345
PFAM:
PF04230
PRIDE:
P71242
PRODB:
PRO_000024216
REFSEQ:
NP_416549
UNIPROT:
P71242


Operon      
Name: wcaKLM         
Operon arrangement:
Transcription unit        Promoter
wcaKLM


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter wcaMp1 2115934 reverse Similarity to the consensus
Read more >
[ICWHO] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Stevenson G., Andrianopoulos K., Hobbs M., Reeves PR., 1996, Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid., J Bacteriol 178(16):4885-93

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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