RegulonDB

Gene
Name:	yfcC
Synonym(s):	ECK2292, G7190, b2298
Genome position(nucleotides):	2417081 --> 2418601 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	52.07
External database links:

ASAP:	ABE-0007585
ECHOBASE:	EB2491
ECOLIHUB:	yfcC
OU-MICROARRAY:	b2298
STRING:	511145.b2298
COLOMBOS:	yfcC

Product

Name:

putative transporter YfcC

Synonym(s):

YfcC

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

54.797

Isoelectric point:

7.146

Motif(s):

Type	Positions	Sequence
	419 -> 439	SGQAALTMPLLAPLGDLVGVN
	86 -> 90	GDERP
	107 -> 127	GTAVGIIMFMLVIGGAFGIVM
	442 -> 462	VTVLAFQFGDGFSHIIYPTSA
	15 -> 501	MPDTLVIIFFVAILTSLATWVVPVGMFDSQEVQYQVDGQTKTRKVVDPHSFRILTNEAGEPEYHRVQLFTTGDERPGLMNFPFEGLTSGSKYGTAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRHTRGNEILFIPALFILFSLGGAVFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQGIAGVPVLSGSGLRIVVWVIATLIGLIFTMVYASRVKKNPLLSRVHESDRFFREKQADVEQRPFTFGDWLVLIVLTAVMVWVIWGVIVNAWFIPEIASQFFTMGLVIGIIGVVFRLNGMTVNTMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGDASVLNTILNSIANAISGLDNAVAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFGDGFSHIIYPTSASLMATLGVCRVDFRNWLKVGATLLGLLFIMSSVVVIGAQ

Classification:

Multifun Terms (GenProtEC)
		4 - transport --> 4.9.B - Putative uncharacterized transport protein
		6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0016021 - integral component of membrane
	molecular_function	GO:0015297 - antiporter activity
	biological_process	GO:0055085 - transmembrane transport

Note(s):

Note(s): ...[more].

Reference(s):

[1] Jindal S., et al., 2019
[2] Wang X., et al., 2014

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PFAM:

PRIDE:

REFSEQ:

UNIPROT:

Operon

Name:

yfcC

Operon arrangement:

Transcription unit	Promoter
yfcC

RNA cis-regulatory element

Attenuation:	Transcriptional

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_2604	2415098	forward	nd	[RS-EPT-CBR]	[3]
promoter	TSS_2605	2415351	forward	nd	[RS-EPT-CBR]	[3]
promoter	TSS_2606 (cluster)	2415354	forward	For this promoter, there is a cluster of 2 transcription start sites,in the interval 2415354 to 2415355, where the highest frequency is at position 2413376. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[3]
promoter	TSS_2607	2415750	forward	nd	[RS-EPT-CBR]	[3]
promoter	TSS_2608	2415781	forward	nd	[RS-EPT-CBR]	[3]
promoter	TSS_2609	2415814	forward	nd	[RS-EPT-CBR]	[3]
promoter	TSS_2610	2415818	forward	nd	[RS-EPT-CBR]	[3]
promoter	TSS_2611	2416038	forward	nd	[RS-EPT-CBR]	[3]
promoter	TSS_2612	2416149	forward	nd	[RS-EPT-CBR]	[3]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195
[2] Wang X., Gao P., Xu G., 2014, [Hydrophilic interaction liquid chromatography coupled with mass spectrometry for metabolomic analysis of Escherichia coli]., Se Pu 32(10):1084-93
[3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.