RegulonDB RegulonDB 11.1: Gene Form
   

eutA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

eutA eutH eutG yffS eutJ TSS_2748 TSS_2748

Gene      
Name: eutA    Texpresso search in the literature
Synonym(s): ECK2446, G7281, b2451, yffT
Genome position(nucleotides): 2565481 <-- 2566884
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
59.12
External database links:  
ASAP:
ABE-0008079
ECHOBASE:
EB3933
ECOLIHUB:
eutA
OU-MICROARRAY:
b2451
STRING:
511145.b2451
COLOMBOS: eutA


Product      
Name: ethanolamine ammonia-lyase reactivase EutA
Synonym(s): EutA, YffT, reactivating factor for ethanolamine ammonia-lyase
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 49.599
Isoelectric point: 5.397
Motif(s):
 
Type Positions Sequence Comment
5 -> 465 QLLSVGIDIGTTTTQVIFSRLELVNRAAVSQVPRYEFIKREISWQSPVFFTPVDKQGGLKEAELKTLILEQYHAAGIEPESVDSGAIIITGESAKTRNARPAVMALSQSLGDFVVASAGPHLESVIAGHGAGAQTLSEQRLCRVLNIDIGGGTANYALFDAGKISGTACLNVGGRLLETDSHGRVVYAHKPGQMIVDECFGAGTDARSLTGAQLVQVTRRMAELIVEVIDGTLSPLAQALMQTGLLPAGVTPEIITLSGGVGECYRHQPADPFCFADIGPLLATALHDHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEGVQLPLRNLPVAIPIDETDLVGAWQQALIQLDLDPKTDAYVLALPASLPVRYAAVLTVINALVDFVARFPNPHPLLVVAGQDFGKALGMLLRPQLQQLPLAVIDEVIVRAGDYIDIGTPLFGGSVVPVTVKSLAF

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.4 - amines
  2 - information transfer --> 2.3 - protein related --> 2.3.4 - chaperoning, repair (refolding)
Gene Ontology Terms (GO)  
cellular_component GO:0005886 - plasma membrane
biological_process GO:0030091 - protein repair
GO:0046336 - ethanolamine catabolic process
GO:0051349 - positive regulation of lyase activity
Note(s): Note(s): ...[more].
Evidence: [EXP-IDA-PURIFIED-PROTEIN] Assay of protein purified to homogeneity
Reference(s): [1] Mori K., et al., 2004
External database links:  
ALPHAFOLD:
P76551
DIP:
DIP-9527N
ECOCYC:
G7281-MONOMER
ECOLIWIKI:
b2451
INTERPRO:
IPR009377
INTERPRO:
IPR043129
PFAM:
PF06277
PRIDE:
P76551
PRODB:
PRO_000022535
REFSEQ:
NP_416946
UNIPROT:
P76551


Operon      
Name: eutHA         
Operon arrangement:
Transcription unit        Promoter
eutHA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2748 2564868 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Mori K., Bando R., Hieda N., Toraya T., 2004, Identification of a reactivating factor for adenosylcobalamin-dependent ethanolamine ammonia lyase., J Bacteriol 186(20):6845-54

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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