RegulonDB

Gene
Name:	ygaV
Synonym(s):	ECK2661, G7397, b2667
Genome position(nucleotides):	2797211 --> 2797510
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	53.0
External database links:

ASAP:	ABE-0008784
ECHOBASE:	EB3296
ECOLIHUB:	ygaV
OU-MICROARRAY:	b2667
STRING:	511145.b2667
COLOMBOS:	ygaV

Product

Name:

putative DNA-binding transcriptional regulator YgaV

Synonym(s):

YgaV

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

10.596

Isoelectric point:

8.756

Motif(s):

Type	Positions	Sequence	Comment
	7 -> 99	LQASAEQAAALLKAMSHPKRLLILCMLSGSPGTSAGELTRITGLSASATSQHLARMRDEGLIDSQRDAQRILYSIKNEAVNAIIATLKNVYCP	UniProt: HTH arsR-type.
	23 -> 70	HPKRLLILCMLSGSPGTSAGELTRITGLSASATSQHLARMRDEGLIDS
	41 -> 60	AGELTRITGLSASATSQHLA	UniProt: H-T-H motif.

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		3 - regulation --> 3.1 - type of regulation --> 3.1.2 - transcriptional level
Gene Ontology Terms (GO)
	cellular_component	GO:0005829 - cytosol
	molecular_function	GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity
	biological_process	GO:0006355 - regulation of transcription, DNA-templated

Note(s):

Note(s): ...[more].

Evidence:

[COMP-AINF-FN-FROM-SEQ] Automated inference of function from sequence
[EXP-IMP] Inferred from mutant phenotype

Reference(s):

[1] Gueune H., et al., 2008
[2] Perez-Rueda E., et al., 2004

External database links:

ALPHAFOLD:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PDB:

PFAM:

PRIDE:

PRINTS:

PROSITE:

REFSEQ:

SMART:

SMR:

UNIPROT:

Operon

Name:

ygaVP

Operon arrangement:

Transcription unit	Promoter
ygaVP

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_2989	2797187		forward	nd	[RS-EPT-CBR]	[3]
	promoter	TSS_2990	2797266		forward	nd	[RS-EPT-CBR]	[3]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Gueune H., Durand MJ., Thouand G., DuBow MS., 2008, The ygaVP genes of Escherichia coli form a tributyltin-inducible operon., Appl Environ Microbiol 74(6):1954-8
[2] Perez-Rueda E., Collado-Vides J., Segovia L., 2004, Phylogenetic distribution of DNA-binding transcription factors in bacteria and archaea., Comput Biol Chem 28(5-6):341-50
[3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.