RegulonDB RegulonDB 11.1: Gene Form
   

ygcS gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ygcU ygcS ygcQ ygcR

Gene      
Name: ygcS    Texpresso search in the literature
Synonym(s): ECK2766, G7437, b2771
Genome position(nucleotides): 2896533 <-- 2897870
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 53.21
External database links:  
ASAP:
 ABE-0009082
ECHOBASE:
 EB2927
ECOLIHUB:
 ygcS
MIM:
 212140
OU-MICROARRAY:
 b2771
STRING:
 511145.b2771
COLOMBOS: ygcS


Product      
Name: putative transporter YgcS
Synonym(s): YgcS
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 48.234
Isoelectric point: 9.677
Motif(s):
 
Type Positions Sequence Comment
23 -> 43 LTFGAHLTDGYVLGVIGYAII UniProt: Helical; Name=1.
29 -> 429 LTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPL
57 -> 77 GMIGGSALLGLFLGSLVLGWI UniProt: Helical; Name=2.
86 -> 106 IFTFSFLLITLASFLQFFATT UniProt: Helical; Name=3.
115 -> 135 ILIGIGLGGDYSVGHTLLAEF UniProt: Helical; Name=4.

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
biological_process GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ALPHAFOLD:
 Q46909
ECOCYC:
 B2771-MONOMER
ECOLIWIKI:
 b2771
INTERPRO:
 IPR036259
INTERPRO:
 IPR042471
INTERPRO:
 IPR020846
INTERPRO:
 IPR005829
INTERPRO:
 IPR005828
MODBASE:
 Q46909
PFAM:
 PF00083
PRIDE:
 Q46909
PROSITE:
 PS00217
PROSITE:
 PS50850
REFSEQ:
 NP_417251
UNIPROT:
 Q46909


Operon      
Name: ygcS         
Operon arrangement:
Transcription unit        Promoter
ygcS


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

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