Gene
Name:	mlaB
Synonym(s):	ECK3180, G7658, b3191, yrbB
Genome position(nucleotides):	3336963 <-- 3337256
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	53.4
External database links:

ASAP:	ABE-0010487
ECHOBASE:	EB2649
ECOLIHUB:	mlaB
OU-MICROARRAY:	b3191
STRING:	511145.b3191
COLOMBOS:	mlaB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_3501 (cluster)	3336555	reverse	nd	[RS-EPT-CBR]	[5]
promoter	ibaGp9	3336954	reverse	nd	[COMP-AINF]	[6]
promoter	ibaGp4	3336983	reverse	nd	[COMP-AINF]	[6]
promoter	TSS_3502	3337936	reverse	nd	[RS-EPT-CBR]	[5]
promoter	TSS_3503	3338185	reverse	nd	[RS-EPT-CBR]	[5]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates
[COMP-AINF] Inferred computationally without human oversight

Reference(s)
[1] Coudray N., Isom GL., MacRae MR., Saiduddin MN., Bhabha G., Ekiert DC., 2020, Structure of bacterial phospholipid transporter MlaFEDB with substrate bound., Elife 9
[2] Ekiert DC., Bhabha G., Isom GL., Greenan G., Ovchinnikov S., Henderson IR., Cox JS., Vale RD., 2017, Architectures of Lipid Transport Systems for the Bacterial Outer Membrane., Cell 169(2):273-285.e17
[3] Hughes GW., Hall SCL., Laxton CS., Sridhar P., Mahadi AH., Hatton C., Piggot TJ., Wotherspoon PJ., Leney AC., Ward DG., Jamshad M., Spana V., Cadby IT., Harding C., Isom GL., Bryant JA., Parr RJ., Yakub Y., Jeeves M., Huber D., Henderson IR., Clifton LA., Lovering AL., Knowles TJ., 2019, Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system., Nat Microbiol 4(10):1692-1705
[4] Kolich LR., Chang YT., Coudray N., Giacometti SI., MacRae MR., Isom GL., Teran EM., Bhabha G., Ekiert DC., 2020, Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation., Elife 9
[5] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.
[6] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

Transcriptional Regulation
	Display Regulation
Activated by:	MarA