RegulonDB RegulonDB 10.9: Gene Form
   

ibsC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

serA fau sibC ibsC SibC TSS_3200 TSS_3200 TSS_3199 TSS_3199 TSS_3198 TSS_3198 TSS_3197 TSS_3197 TSS_3196 TSS_3196 TSS_3195 TSS_3195 TSS_3194 TSS_3194 TSS_3193 TSS_3193 sibCp sibCp

Gene      
Name: ibsC    Texpresso search in the literature
Synonym(s): ECK4480, G0-10631, b4665
Genome position(nucleotides): 3056890 <-- 3056949 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
35.0
External database links:  
ECOLIHUB:
ibsC
COLOMBOS: ibsC


Product      
Name: toxic peptide IbsC
Synonym(s): IbsC
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 2.209
Isoelectric point: 9.355
Motif(s):
 
Type Positions Sequence
1 -> 19 MMRLVIILIVLLLISFSAY
2 -> 18 MRLVIILIVLLLISFSA

 

Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes
Gene Ontology Terms (GO)  
cellular_component GO:0005887 - integral component of plasma membrane
biological_process GO:0012501 - programmed cell death
Note(s): Note(s): ...[more].
Evidence: [IMP] Inferred from mutant phenotype
Reference(s): [1] Fozo EM., et al., 2008
[2] Mok WW., et al., 2009
External database links:  
ECOCYC:
MONOMER0-2857
INTERPRO:
IPR025881
PFAM:
PF13956
PRIDE:
C1P615
PRODB:
PRO_000022985
REFSEQ:
YP_002791255
UNIPROT:
C1P615


Operon      
Name: ibsC         
Operon arrangement:
Transcription unit        Promoter
ibsC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3193 3057340 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3194 3057467 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3195 3057593 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3196 3057726 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3197 3057734 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3198 3058242 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3199 3058303 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3200 3058379 reverse nd [RS-EPT-CBR] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Fozo EM., Kawano M., Fontaine F., Kaya Y., Mendieta KS., Jones KL., Ocampo A., Rudd KE., Storz G., 2008, Repression of small toxic protein synthesis by the Sib and OhsC small RNAs., Mol Microbiol 70(5):1076-93

 [2] Mok WW., Navani NK., Barker C., Sawchyn BL., Gu J., Pathania R., Zhu RD., Brown ED., Li Y., 2009, Identification of a toxic peptide through bidirectional expression of small RNAs., Chembiochem 10(2):238-41

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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