RegulonDB

Gene
Name:	mntS
Synonym(s):	ECK4517, G0-10715, G0-8881, b4705
Genome position(nucleotides):	852869 <-- 852997 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	41.09

Product

Name:

small protein MntS

Synonym(s):

MntS

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

5.031

Isoelectric point:

10.218

Classification:

Multifun Terms (GenProtEC)
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm
	biological_process	GO:0030026 - cellular manganese ion homeostasis GO:0071287 - cellular response to manganese ion

Note(s):

Note(s): ...[more].

Evidence:

[IMP] Inferred from mutant phenotype

Reference(s):

External database links:

ECOCYC:

PRIDE:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

rybA-mntS

Operon arrangement:

Transcription unit	Promoter
rybA-mntS	rybAp

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	ybiPp5	852626	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 6.653. P-value: 3.013e-5 Read more >	[ICWHO]	[4]
promoter	TSS_978	853047	reverse	nd	[RS-EPT-CBR]	[5]
promoter	mntRp6	853080	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.936. P-value: 6.773e-5 Read more >	[ICWHO]	[4]
promoter	mntRp5	853083	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.1. P-value: 4.632e-5 Read more >	[ICWHO]	[4]
promoter	mntRp4	853135	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 3.883. P-value: 6.910e-5 Read more >	[ICWHO]	[4]
promoter	TSS_979	853137	forward	nd	[RS-EPT-CBR]	[5]

Evidence
[ICWHO] Inferred computationally without human oversight
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Duval M., Cossart P., 2017, Small bacterial and phagic proteins: an updated view on a rapidly moving field., Curr Opin Microbiol 39:81-88
[2] Martin JE., Waters LS., Storz G., Imlay JA., 2015, The Escherichia coli small protein MntS and exporter MntP optimize the intracellular concentration of manganese., PLoS Genet 11(3):e1004977
[3] PLOS Genetics Staff., 2015, Correction: The Escherichia coli Small Protein MntS and Exporter MntP Optimize the Intracellular Concentration of Manganese., PLoS Genet 11(6):e1005322
[4] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78
[5] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.