RegulonDB RegulonDB 11.1: Gene Form
   

rbsA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

rbsA rbsC rbsD RybB TSS_4364 (cluster) TSS_4364 (cluster) TSS_4363 (cluster) TSS_4363 (cluster) TSS_4362 TSS_4362 TSS_4361 TSS_4361 TSS_4360 TSS_4360

Gene      
Name: rbsA    Texpresso search in the literature
Synonym(s): ECK3743, EG10814, b3749, rbsP, rbsT
Genome position(nucleotides): 3933778 --> 3935283
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.2
External database links:  
ASAP:
 ABE-0012259
CGSC:
 12082
ECHOBASE:
 EB0807
ECOLIHUB:
 rbsA
OU-MICROARRAY:
 b3749
STRING:
 511145.b3749
COLOMBOS: rbsA


Product      
Name: ribose ABC transporter ATP binding subunit
Synonym(s): RbsA, RbsP, RbsT
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 55.042
Isoelectric point: 5.995
Motif(s):
 
Type Positions Sequence Comment
5 -> 241 LQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFLGREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQFIAEREVASLTEDSLIEMMVGRK UniProt: ABC transporter 1.
22 -> 169 GAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFLGREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFESKVIIMDEPT
37 -> 44 GENGAGKS UniProt: ATP.
43 -> 43 K UniProt: Loss of transport..
162 -> 169 VIIMDEPT

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.a - ABC superfamily ATP binding cytoplasmic component
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
molecular_function GO:0005515 - protein binding
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0015407 - ABC-type monosaccharide transporter activity
GO:0015591 - D-ribose transmembrane transporter activity
GO:0015611 - ABC-type D-ribose transporter activity
biological_process GO:0008643 - carbohydrate transport
GO:0015752 - D-ribose transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P04983
DIP:
 DIP-10640N
ECOCYC:
 RBSA-MONOMER
ECOLIWIKI:
 b3749
INTERPRO:
 IPR017871
INTERPRO:
 IPR027417
INTERPRO:
 IPR015861
INTERPRO:
 IPR003593
INTERPRO:
 IPR003439
MODBASE:
 P04983
PFAM:
 PF00005
PRIDE:
 P04983
PRODB:
 PRO_000023682
PROSITE:
 PS51254
PROSITE:
 PS00211
PROSITE:
 PS50893
REFSEQ:
 NP_418205
SMART:
 SM00382
SMR:
 P04983
UNIPROT:
 P04983


Operon      
Name: rbsDACBKR         
Operon arrangement:
Transcription unit        Promoter
rbsDACBKR


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: RbsR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4360 3935432 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4361 3936137 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4362 3936145 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4363 (cluster) 3936163 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4364 (cluster) 3936177 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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