RegulonDB RegulonDB 11.1: Gene Form
   

rbsC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

rbsA rbsC rbsB rbsZ RybB TSS_4365 TSS_4365 TSS_4364 (cluster) TSS_4364 (cluster) TSS_4363 (cluster) TSS_4363 (cluster) TSS_4362 TSS_4362 TSS_4361 TSS_4361 TSS_4360 TSS_4360

Gene      
Name: rbsC    Texpresso search in the literature
Synonym(s): ECK3744, EG10816, b3750, rbsP, rbsT
Genome position(nucleotides): 3935288 --> 3936253
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 53.42
External database links:  
ASAP:
 ABE-0012261
CGSC:
 12089
ECHOBASE:
 EB0809
ECOLIHUB:
 rbsC
OU-MICROARRAY:
 b3750
STRING:
 511145.b3750
COLOMBOS: rbsC


Product      
Name: ribose ABC transporter membrane subunit
Synonym(s): RbsC, RbsP, RbsT
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 33.452
Isoelectric point: 10.218
Motif(s):
 
Type Positions Sequence Comment
23 -> 43 LIALLVLIAIVSTLSPNFFTI UniProt: Helical.
45 -> 313 NLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADLFGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLA
57 -> 77 AIMAVGMTLVILTSGIDLSVG UniProt: Helical.
126 -> 145 AFIATLVMMLLLRGVTMVYT UniProt: Helical.
169 -> 190 PLGVPTPVWIMGIVFLAAWYML UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
  6 - cell structure --> 6.1 - membrane
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.m - ABC superfamily, membrane component
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
molecular_function GO:0005515 - protein binding
GO:0015591 - D-ribose transmembrane transporter activity
GO:0022857 - transmembrane transporter activity
biological_process GO:0008643 - carbohydrate transport
GO:0015752 - D-ribose transmembrane transport
GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Park Y., et al., 1999
External database links:  
ALPHAFOLD:
 P0AGI1
ECOCYC:
 RBSC-MONOMER
ECOLIWIKI:
 b3750
INTERPRO:
 IPR001851
PFAM:
 PF02653
PRIDE:
 P0AGI1
PRODB:
 PRO_000023684
REFSEQ:
 NP_418206
SMR:
 P0AGI1
UNIPROT:
 P0AGI1


Operon      
Name: rbsDACBKR         
Operon arrangement:
Transcription unit        Promoter
rbsDACBKR


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: RbsR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4360 3935432 forward nd [RS-EPT-CBR] [2]
  promoter TSS_4361 3936137 forward nd [RS-EPT-CBR] [2]
  promoter TSS_4362 3936145 forward nd [RS-EPT-CBR] [2]
  promoter TSS_4363 (cluster) 3936163 forward nd [RS-EPT-CBR] [2]
  promoter TSS_4364 (cluster) 3936177 forward nd [RS-EPT-CBR] [2]
  promoter TSS_4365 3936260 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Park Y., Park C., 1999, Topology of RbsC, a membrane component of the ribose transporter, belonging to the AraH superfamily., J Bacteriol 181(3):1039-42

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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