RegulonDB

Gene
Name:	tus
Synonym(s):	ECK1605, EG11038, b1610, tau
Genome position(nucleotides):	1684259 --> 1685188
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	50.75
External database links:

ASAP:	ABE-0005378
CGSC:	17800
ECHOBASE:	EB1031
ECOLIHUB:	tus
OU-MICROARRAY:	b1610
STRING:	511145.b1610
COLOMBOS:	tus

Product

Name:

DNA replication terminus site-binding protein

Synonym(s):

DNA-binding protein; inhibition of replication at Ter sites, TBP, Tau, Tus, ter-binding protein

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

35.783

Isoelectric point:

10.087

Motif(s):

Type	Positions	Sequence	Comment
	9 -> 306	RLNTTFRQMEQELAIFAAHLEQHKLLVARVFSLPEVKKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQVDNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRTLTVLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQDIAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGELLNYDADNVQHRYKPQAQPLRLIIPRLHLY
	85 -> 102	NRSSKAAVRLPGVLCYQV	UniProt: In Ref. 6; CAA27699..
	121 -> 122	KT	UniProt: In Ref. 6; CAA27699..
	134 -> 134	L	UniProt: In Ref. 6; CAA27699..
	150 -> 150	L	UniProt: In Ref. 6; CAA27699..

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		2 - information transfer --> 2.1 - DNA related --> 2.1.1 - DNA replication
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm GO:0005829 - cytosol
	molecular_function	GO:0003677 - DNA binding GO:0043565 - sequence-specific DNA binding
	biological_process	GO:0006260 - DNA replication GO:0006274 - DNA replication termination GO:0071807 - replication fork arrest involved in DNA replication termination

Note(s):

Note(s): ...[more].

Evidence:

[EXP-IDA-PURIFIED-PROTEIN] Assay of protein purified to homogeneity

Reference(s):

[1] Skokotas A., et al., 1994

External database links:

ALPHAFOLD:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

MINT:

MODBASE:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PFAM:

PRIDE:

PRODB:

REFSEQ:

SMR:

UNIPROT:

Reference(s)
[1] Skokotas A., Wrobleski M., Hill TM., 1994, Isolation and characterization of mutants of Tus, the replication arrest protein of Escherichia coli., J Biol Chem 269(32):20446-55
[2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78